Targeting Survivin DC Cells (Tricision) in Glioblastoma: NCT07715097 Clinical Landscape Report 2026
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This Clinical Landscape Report was built with PatSnap Life Sciences MCP workflows. Clinical Trials MCP supplies protocol and result records, Drug & Asset MCP adds asset context, and Company & Deal Intelligence MCP resolves sponsor background. Use the same structured MCP building blocks in your research workflow.
Data snapshot: 11 September 2026. This strategic research report is not medical, regulatory or investment advice. Trial status and dates can change.
Phase 2
Clinical phase
Not yet recruiting
Recruitment status
30
Planned enrollment
2028-09-30
Primary-completion proxy
Executive view
NCT07715097 evaluates Targeting Survivin DC Cells (Tricision) in Glioblastoma. The disclosed sponsor is Beijing Tricision Therapeutics Co., Ltd., the design is Interventional, and the geographic footprint is Geography not reported. The first listed primary endpoint is Primary Outcome Measure:Overall Survival (OS), assessed over From the date of glioblastoma (GBM) surgery until death from any cause, assessed up to 36 months..
The key landscape question is whether this protocol can generate a clinically interpretable signal relative to nearby programs. Phase alone is not a measure of evidence quality. Endpoint relevance, comparator choice, masking, enrollment feasibility, patient selection, country coverage and follow-up must be considered together.
PatSnap MCP Servers make this assessment reproducible by keeping protocol facts, result evidence, asset attributes and sponsor identity in separate structured calls.
How the MCP evidence stack was assembled
Clinical Trials MCP clinical_trial_fetch retrieved the design, outcomes, phase, status, enrollment, sponsor, countries and timing for NCT07715097 and selected peers. clinical_trial_result_fetch supplied detailed result records from the wider Glioblastoma landscape. Drug & Asset MCP drug_fetch was queried for Targeting Survivin DC Cells (Tricision), while Company & Deal Intelligence MCP organization_fetch was queried for Beijing Tricision Therapeutics Co., Ltd..
This separation reduces a common diligence error: treating a registry label, a company description or a result excerpt as if each represented the complete evidence package. Explore the source workflow at the PatSnap MCP marketplace.
Trial landscape table
| Trial | Asset / intervention | Phase / status | Sponsor | Geography | Primary endpoint | Readout proxy |
|---|---|---|---|---|---|---|
| NCT07715097 | Targeting Survivin DC Cells (Tricision) | Phase 2 / Not yet recruiting | Beijing Tricision Therapeutics Co., Ltd. | Geography not reported | Primary Outcome Measure:Overall Survival (OS) From the date of glioblastoma (GBM) surgery until death from any caus… | 2028-09-30 |
| NCT07811297 | Anlotinib Dihydrochloride | Phase 1/2 / Not yet recruiting | Advenchen Laboratories LLC | United States | Recommended combination dose (RCD) 36 months | 2030-09-01 |
| NCT07758062 | Temozolomide | Phase 2 / Not yet recruiting | Tianjin Medical University General Hospital | China | Progression-Free Survival (PFS) Up to 24 months | 2029-08-01 |
| NCT07754734 | Temozolomide | Phase 2 / Not yet recruiting | Dongguan People's Hospital | Geography not reported | Progression-Free Survival（PFS） From date of randomization until the date of first documented progres… | 2029-07-31 |
| NCT07751744 | JBI-778 | Phase 1/2 / Not yet recruiting | Jubilant Therapeutics, Inc. | Geography not reported | Phase 1 - Incidence of Dose Limiting Toxicities (DLTs) At the end of Cycle 1 (each cycle is 21 days) | 2030-03-31 |
The table aligns endpoints, sponsors, phases, geographies and readout proxies. It is descriptive, not a head-to-head efficacy comparison. Differences in population, baseline risk, intervention schedule and follow-up can dominate apparent cross-trial differences.
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Protocol design and endpoint interpretation
NCT07715097 is a Phase 2, not yet recruiting study with 30 planned participants. Allocation is N/A, masking is None (Open Label), and the intervention model is Single Group Assignment.
The primary endpoint is “Primary Outcome Measure:Overall Survival (OS)” over “From the date of glioblastoma (GBM) surgery until death from any cause, assessed up to 36 months..” No additional primary-endpoint description was returned in the selected field set.
Interpretation should test whether the endpoint captures a clinically meaningful change, whether its time horizon matches the proposed biology, and whether treatment discontinuation or missing data can bias the estimate. The planned enrollment of 30 should be assessed against expected effect size, event frequency, multiplicity, subgroup plans and attrition.
No named control drug was returned in the protocol field set. A placebo comparator can strengthen internal efficacy assessment, while an active comparator may better test clinical differentiation. Single-arm and open-label programs require greater weight on objective outcomes, independent assessment and external benchmarks.
Indexed readouts in the surrounding landscape
5 recent result records were selected as contextual evidence for Glioblastoma. These records do not establish direct evidence for NCT07715097 unless the registration number matches.
Phase 1 dose-escalation trial combining sulfasalazine and stereotactic radiosurgery in patients with recurrent glioblastoma
Phase 1; n=12; AE = Of 20 adverse events, two were grade 3 (transient lymphocytopenia), four grade 2, and fourteen grade 1 ; AE = Of 20 adverse events, two were grade 3 (transient lymphocytopenia), four grade 2, and fourteen grade 1 Source: https://pubmed.ncbi.nlm.nih.gov/42229231/
Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy Versus Conventional Photon Irradiation With Concomitant and Adjuvant Temozolomide i…
Phase 2; n=624; Median Survival Time (Within Center Group)(Median): Cox Proportional Hazard = 0.95(70% CI, 0.81 - 1.10), P-Value = 0.25; Cox Proportional Hazard = 0.81(70% CI, 0.67 - 0.98), P-Value = 0.11; Median Survival Time (Within Center Group)(Median) = 22.8 months (95% Confidence Interval, 20.0 - 28.6) Source: https://clinicaltrials.gov/ct2/show/results/NCT02179086
A First-in-Human Clinical Trial of Pharmacologic Ascorbate and Ferumoxytol Combined With Concomitant Temozolomide and External Beam Radiation Therapy for Newly Diagnosed Glioblast…
Phase 1; n=16; Number of Ferumoxytol-related Dose Limiting Toxicities (DLTs) = 2 Dose Limiting Toxicities ; Number of Ferumoxytol-related Dose Limiting Toxicities (DLTs) = 0 Dose Limiting Toxicities Source: https://clinicaltrials.gov/ct2/show/results/NCT04900792
Result fields should be reconciled with the source record before quantitative comparison. Population definitions, analysis sets, dose cohorts, estimands, confidence intervals, rescue therapy and follow-up can materially change the meaning of a numerical endpoint. Clinical Trials MCP supports repeatable refreshes as result records change.
Asset and sponsor context
Targeting Survivin DC Cells (Tricision) is indexed as Therapeutic vaccine with survivin biology and a global stage of Phase 2. The asset profile lists Qichensheng Biotechnology (Zhuhai) Co., Ltd. as an originator or developer.
Beijing Tricision Therapeutics Co., Ltd. is indexed in China with the website http://www.tricisionbio.com. The organization record is used to resolve sponsor identity. The record lists 27 development-stage drug assets.
For execution diligence, monitor sponsor ownership, collaborator additions, site expansion, protocol amendments and enrollment revisions. A change in ownership or geography can alter operational confidence as well as the commercial meaning of a future readout.
Development white space
- Endpoint white space. Determine whether a more patient-relevant outcome, longer durability window or blinded central assessment would resolve uncertainty left by the current endpoint.
- Population white space. Test biomarker-defined, treatment-line or risk-stratified subgroups where effect size and unmet need could be clearer.
- Comparator white space. Identify whether the study can support differentiation against the current standard of care rather than only activity against baseline or placebo.
- Geographic white space. Assess whether the disclosed footprint supports recruitment, regulatory transferability and commercial generalizability.
- Sequencing white space. Clarify whether Targeting Survivin DC Cells (Tricision) is intended for monotherapy, combination, maintenance, rescue or an earlier treatment line.
White space should be framed as an unanswered development question, not merely an unoccupied mechanism label. A credible program closes a measurable clinical uncertainty with a design that can be executed and interpreted.
Strategic implications and next readouts
For sponsors, the endpoint hierarchy, safety window, enrollment pace and protocol amendment history should all support the same target product profile. Advancement criteria should be set before the readout and tied to clinical effect, uncertainty, tolerability and operational feasibility.
For business-development teams, differentiation may come from a sharper population, stronger comparator, more durable benefit, simpler delivery or clearer sequencing role. For investors, the central risk is evidence quality relative to time and capital, not the phase label in isolation.
Track recruitment status, enrollment changes, primary-completion timing, endpoint revisions, new result records, sponsor ownership and collaborator changes. Re-run the PatSnap MCP workflow when a surrogate becomes a clinical outcome, a single-country study expands, the comparator changes or a new result materially shifts the competitive benchmark.
Source trail and bottom line
Anchor trial: NCT07715097
Protocol source: https://clinicaltrials.gov/study/NCT07715097
MCP sources: Clinical Trials MCP (clinical_trial_fetch and clinical_trial_result_fetch); Drug & Asset MCP (drug_fetch); Company & Deal Intelligence MCP (organization_fetch).
Data snapshot: 11 September 2026.
Targeting Survivin DC Cells (Tricision) in Glioblastoma is best understood through the interaction of protocol design, surrounding readouts, asset context and sponsor execution. The current record makes Primary Outcome Measure:Overall Survival (OS) and 2028-09-30 the leading decision points.
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