Last update 11 Jul 2026

THAL-NVP-2-03-084

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
THAL-NVP-2-03-084
Target
CDK9
Action
degraders
Mechanism
CDK9 degraders(Cyclin-dependent kinase 9 degraders)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Harvard Medical SchoolHarvard Medical School
Active Organization-
Inactive Organization
Harvard Medical SchoolHarvard Medical SchoolDana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.ActivX Biosciences, Inc.
+ [1]
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC44H53ClN10O6
InChIKeyGKWDSIRGBSJWQV-WIYXFFCHSA-N
CAS Registry2207587-86-6

Related

100 Clinical Results associated with THAL-NVP-2-03-084
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100 Translational Medicine associated with THAL-NVP-2-03-084
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100 Patents (Medical) associated with THAL-NVP-2-03-084
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100 Deals associated with THAL-NVP-2-03-084
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Harvard Medical SchoolHarvard Medical School
18 Dec 2017
NeoplasmsPreclinical
United States
ActivX Biosciences, Inc.
18 Dec 2017
NeoplasmsPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
18 Dec 2017
NeoplasmsPreclinical
United States
Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
18 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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