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Last update 13 Aug 2025
SYH2053
Last update 13 Aug 2025
Overview
Basic Info
Drug Type siRNA |
Synonyms SYH2053 |
Target |
Action inhibitors |
Mechanism PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
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Related
3
Clinical Trials associated with SYH2053CTR20251534
一项在中国低密度脂蛋白胆固醇正常或升高参与者中评价SYH2053注射液对阿托伐他汀钙片药代动力学影响的I期临床试验
[Translation] A phase I clinical trial evaluating the effect of SYH2053 injection on the pharmacokinetics of atorvastatin calcium tablets in Chinese participants with normal or elevated low-density lipoprotein cholesterol
CTR20244336
一项多中心、随机、双盲、安慰剂及阳性药对照，评价在背景治疗的基础上不同剂量SYH2053注射液对中国原发性高胆固醇血症或混合血脂异常参与者的疗效、安全性的Ⅱ期研究
[Translation] A multicenter, randomized, double-blind, placebo- and active drug-controlled Phase II study to evaluate the efficacy and safety of different doses of SYH2053 injection on the basis of background treatment in Chinese participants with primary hypercholesterolemia or mixed dyslipidemia
NCT06229548
A Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SYH2053 in Subjects With Normal or Elevated Low-Density Lipoprotein Cholesterol
100 Clinical Results associated with SYH2053
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100 Translational Medicine associated with SYH2053
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100 Patents (Medical) associated with SYH2053
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100 Deals associated with SYH2053
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Combined hyperlipidemia | Phase 2 | China | 03 Dec 2024 | |
| Combined hyperlipidemia | Phase 2 | China | 03 Dec 2024 | |
| Primary hypercholesterolemia | Phase 2 | China | 03 Dec 2024 | |
| Primary hypercholesterolemia | Phase 2 | China | 03 Dec 2024 | |
| Hyperlipidemia, Familial Combined | Phase 1 | China | 08 Jan 2024 | |
| Hyperlipidemia, Familial Combined | Phase 1 | China | 08 Jan 2024 |
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