Last update 24 Dec 2025

INCA-035784

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
INCA-035784, INCA035784
Target
CALR x CD3
Action
inhibitors, stimulants
Mechanism
CALR inhibitors(calreticulin inhibitors), CD3 stimulants(T cell surface glycoprotein CD3 stimulants)
Therapeutic Areas
Hemic and Lymphatic Diseases
Active Indication
Myeloproliferative Disorders
Inactive Indication-
Originator Organization
Incyte Corp.Incyte Corp.
Active Organization
Incyte Corp.Incyte Corp.Merus NVMerus NV
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with INCA-035784
NCT07008118
/ RecruitingPhase 1
A Phase 1, Open-Label, Multicenter Study of INCA035784 in Participants With Myeloproliferative Neoplasms
100 Clinical Results associated with INCA-035784
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100 Translational Medicine associated with INCA-035784
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100 Patents (Medical) associated with INCA-035784
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100 Deals associated with INCA-035784
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Myeloproliferative DisordersPhase 1
United States
Incyte Corp.Incyte Corp.
01 Oct 2025
Myeloproliferative DisordersPhase 1
Australia
Incyte Corp.Incyte Corp.
01 Oct 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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