Last update 19 Mar 2026

Aprepitant/Palonosetron

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
QLM2010
Target
HTR3 x NK1R
Action
antagonists
Mechanism
5-HT3 receptor antagonists(5-hydroxytryptamine receptors, ionotropic (HTR3) antagonists), NK1R antagonists(Neurokinin 1 receptor antagonists)
Therapeutic Areas
Other Diseases
Active Indication
Chemotherapy-induced nausea and vomiting
Inactive Indication-
Originator Organization
Qilu Pharmaceutica Hainanco Ltd.Qilu Pharmaceutica Hainanco Ltd.
Active Organization
Qilu Pharmaceutica Hainanco Ltd.Qilu Pharmaceutica Hainanco Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseNDA/BLA
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC23H21F7N4O3
InChIKeyATALOFNDEOCMKK-OITMNORJSA-N
CAS Registry170729-80-3
View All Structures (3)

Related

3
Clinical Trials associated with Aprepitant/Palonosetron
NCT07081256
/ CompletedPhase 3
A Multicenter, Randomized, Double-blind, Double-dummy, Positive-controlled Phase III Trial, to Evaluate the Efficacy and Safety of QLM2010 for Prevention of Chemotherapy-induced Nausea and Vomiting After Highly Emetogenic Chemotherapy
CTR20243278
/ CompletedPhase 1
QLM2010静脉2分钟给药的药代动力学对比研究
[Translation] Comparative study on the pharmacokinetics of QLM2010 after 2-minute intravenous administration
CTR20240259
/ CompletedPhase 1
QLM2010静脉30分钟给药的药代动力学对比研究
[Translation] Comparative study on the pharmacokinetics of QLM2010 administered intravenously over 30 minutes
100 Clinical Results associated with Aprepitant/Palonosetron
Login to view more data
100 Translational Medicine associated with Aprepitant/Palonosetron
Login to view more data
100 Patents (Medical) associated with Aprepitant/Palonosetron
Login to view more data
100 Deals associated with Aprepitant/Palonosetron
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Chemotherapy-induced nausea and vomitingNDA/BLA
China
Qilu Pharmaceutica Hainanco Ltd.Qilu Pharmaceutica Hainanco Ltd.
15 Dec 2025
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free