Last update 29 Aug 2026

LDR1259

Overview

Basic Info

Drug Type
siRNA
Synonyms
LDR-1259
Target
LPA x PCSK9
Action
inhibitors
Mechanism
LPA inhibitors(Lysophosphatidic acid inhibitors), PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication
Hyperlipidemias
Inactive Indication-
Originator Organization
Leaderna Therapeutics Ltd.
Active Organization
Leaderna Therapeutics Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Boost your research with our RNA technology data.
login
or
view full example data
Boost your research with our RNA technology data.

Related

1
Clinical Trials associated with LDR1259
CTR20263270
/ Not yet recruitingPhase 1
一项评估LDR1259注射液在低密度脂蛋白胆固醇正常或轻度升高及脂蛋白(a)升高试验参与者中的安全性、耐受性、药代动力学及药效学特征的随机、双盲、安慰剂对照Ⅰ期临床试验
[Translation] A randomized, double-blind, placebo-controlled phase I clinical trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of LDR1259 injection in participants with normal or mildly elevated LDL cholesterol and elevated lipoprotein (a) levels.
100 Clinical Results associated with LDR1259
Login to view more data
100 Translational Medicine associated with LDR1259
Login to view more data
100 Patents (Medical) associated with LDR1259
Login to view more data
100 Deals associated with LDR1259
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
HyperlipidemiasPhase 1
China
Leaderna Therapeutics Ltd.
24 Aug 2026
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free