Last update 04 Aug 2026

A-CAR028

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
A CAR028
Target
CD33 x CLL-1
Action
inhibitors
Mechanism
CD33 inhibitors(Myeloid cell surface antigen CD33 inhibitors), CLL-1 inhibitors(C-Type lectin domain family 12 member A inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Refractory acute myeloid leukemiaRelapsing acute myeloid leukemiaAcute Myeloid Leukemia
Inactive Indication-
Originator Organization
AbelZeta Pharma, Inc.
Active Organization
Shanghai AbelZeta Ltd.Shanghai AbelZeta Ltd.AbelZeta Pharma, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with A-CAR028
NCT07198867
/ RecruitingPhase 1IIT
A Study of A-CAR028 Treatment in Subjects With Relapsed/ Refractory Acute Myeloid Leukemia
100 Clinical Results associated with A-CAR028
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100 Translational Medicine associated with A-CAR028
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100 Patents (Medical) associated with A-CAR028
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100 Deals associated with A-CAR028
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Refractory acute myeloid leukemiaPhase 1
China
Shanghai AbelZeta Ltd.Shanghai AbelZeta Ltd.
30 Sep 2025
Relapsing acute myeloid leukemiaPhase 1
China
Shanghai AbelZeta Ltd.Shanghai AbelZeta Ltd.
30 Sep 2025
Acute Myeloid LeukemiaPreclinical
United States
AbelZeta Pharma, Inc.
01 Mar 2025
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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