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Clinical Trials associated with Azilsartan mepixetilA Phase II, Multicenter, Randomized, Double-Blind, Active-Controlled, Parallel-Group Study of the Efficacy and Safety of QR12000 Compound Tablets in Patients With Moderate to Severe Essential Hypertension
The purpose of this study is to compare the antihypertensive effect of QR12000 Compound Tablets with its single component, QR01019 potassium salt, and with valsartan in patients with moderate to severe essential hypertension.
QR01019钾盐片与阿齐沙坦酯钾片在中国健康成年志愿者中的相对生物利用度研究
[Translation] Study on the relative bioavailability of QR01019 potassium salt tablets and azilsartan medoxomil potassium tablets in healthy Chinese adult volunteers
1)比较中国健康成年志愿者空腹状态下分别单次口服QR01019钾盐片或阿齐沙坦酯钾片(EDARBI)的药代动力学特征 2)评价中国健康成年志愿者空腹口服QR01019钾盐片相对于阿齐沙坦酯钾片的相对生物利用度 3)观察QR01019钾盐片和阿齐沙坦酯钾片在中国健康成年志愿者中的安全性
[Translation] 1) To compare the pharmacokinetic characteristics of a single oral dose of QR01019 potassium salt tablets or azilsartan medoxomil potassium tablets (EDARBI) in healthy Chinese adult volunteers under fasting conditions 2) To evaluate the relative bioavailability of QR01019 potassium salt tablets compared with azilsartan medoxomil potassium tablets in healthy Chinese adult volunteers under fasting conditions 3) To observe the safety of QR01019 potassium salt tablets and azilsartan medoxomil potassium tablets in healthy Chinese adult volunteers
QR01019钾盐片在中国健康志愿者中单多次口服给药的耐受性和药代动力学研究及进食对单次给药的药代动力学影响研究
[Translation] Study on the tolerability and pharmacokinetics of single and multiple oral administration of QR01019 potassium salt tablets in Chinese healthy volunteers and the effect of food on the pharmacokinetics of single administration
1)评价单次和多次口服、剂量递增给药 QR01019 钾盐片在健康成年志愿者中的安全性、耐受性和药代动力学(PK)特征; 2)评价高脂饮食对健康成年志愿者单次口服 QR01019 钾盐片的药代动力学(PK)和安全性的影响; 3)为后续临床试验的给药方案提供理论依据。
[Translation] 1) To evaluate the safety, tolerability and pharmacokinetic (PK) characteristics of single and multiple oral and escalating doses of QR01019 potassium salt tablets in healthy adult volunteers; 2) To evaluate the effect of a high-fat diet on the pharmacokinetics (PK) and safety of a single oral dose of QR01019 potassium salt tablets in healthy adult volunteers; 3) To provide a theoretical basis for the dosing regimen of subsequent clinical trials.
100 Clinical Results associated with Azilsartan mepixetil
100 Translational Medicine associated with Azilsartan mepixetil
100 Patents (Medical) associated with Azilsartan mepixetil
100 Deals associated with Azilsartan mepixetil