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Last update 23 Mar 2026
ARTS-876
Last update 23 Mar 2026
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms ARTS-876 |
Target |
Action inhibitors |
Mechanism KEAP1 inhibitors(Kelch-like ECH-associated protein 1 inhibitors), Nrf2 inhibitors(Nuclear factor erythroid 2-related factor 2 inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
2
Clinical Trials associated with ARTS-876CTR20250789
评价ARTS-876在局部晚期或转移性非小细胞肺癌（NSCLC）患者中的安全性、耐受性、药代动力学特征和初步抗肿瘤活性的多中心、开放Ia/Ib期临床试验
[Translation] A multicenter, open-label Phase Ia/Ib clinical trial to evaluate the safety, tolerability, pharmacokinetic profile, and preliminary antitumor activity of ARTS-876 in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)
CTR20254663
评价ARTS-876在不可切除或复发转移性延胡索酸水合酶缺陷型肾细胞癌（FH-RCC）患者中的安全性、耐受性、药代动力学特征和初步 抗肿瘤活性的单中心、开放Ib/II期临床研究
[Translation] A single-center, open-label phase Ib/II clinical trial evaluating the safety, tolerability, pharmacokinetic characteristics, and preliminary antitumor activity of ARTS-876 in patients with unresectable or recurrent metastatic fumarate hydratase-deficient renal cell carcinoma (FH-RCC).
100 Clinical Results associated with ARTS-876
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100 Translational Medicine associated with ARTS-876
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100 Patents (Medical) associated with ARTS-876
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100 Deals associated with ARTS-876
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Renal Cell Carcinoma | Phase 1 | China | 02 Dec 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 1 | China | 09 Apr 2025 | |
| Fumarate Hydratase-Deficient Renal Cell Carcinoma | IND Approval | China | 30 Sep 2025 |
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