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Clinical Trials associated with SNH-119014 / Not yet recruitingPhase 2 A Phase 2 Study to Determine the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of SNH-119014 in Adult Subjects With Non-transfusion-dependent Thalassemia
This study is a multicenter study to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of treatment with SNH-119014 in adult participants with non-transfusion-dependent thalassemia. 30 participants with non-transfusion-dependent thalassemia were enrolled.
A Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic of SNH-119014 in Healthy Adult Volunteers
SNH-119014 is an oral small-molecule agonist of pyruvate kinase red blood cell isozyme (PKR) being developed for the treatment of hemolytic anemias. This initial study will characterize the safety, tolerability and the pharmacokinetics/pharmacodynamics (PK/PD) of a single ascending dose and multiple ascending doses of SNH-119014 in the context of Phase 1 studies in healthy volunteers. The effects of food on the absorption of SNH-119014 will also be evaluated in healthy volunteers.
/ Not yet recruitingPhase 2 SNH-119014片治疗地中海贫血患者的安全性、有效性及药代动力学/药效学的IIa期研究
[Translation] A Phase IIa study of the safety, efficacy, and pharmacokinetic/pharmacodynamic properties of SNH-119014 tablets in the treatment of thalassemia patients.
评价SNH-119014片用于治疗非输血依赖型地中海贫血患者的安全性、有效性和药代动力学特征
[Translation] Evaluation of the safety, efficacy, and pharmacokinetic characteristics of SNH-119014 tablets for the treatment of transfusion-independent thalassemia patients.
100 Clinical Results associated with SNH-119014
100 Translational Medicine associated with SNH-119014
100 Patents (Medical) associated with SNH-119014
100 Deals associated with SNH-119014