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Clinical Trials associated with F-02-2-Na / Not yet recruitingPhase 1 F-02-2-Na片在成年受试者中的I期临床试验研究
[Translation] Phase I clinical trial of F-02-2-Na tablets in adult subjects
主要目的: 1.评估成年受试者单次口服 F-02-2-Na 片后的药动学特征; 2.评估成年受试者单次口服 F-02-2-Na 片后的安全性。
次要目的:
1.评估食物对F-02-2-Na片药代动力学特征的影响;
2.评估成年受试者单次口服 F-02-2-Na 片后的效应:sUA变化的绝对值、百分比值、达标率(≤360 μmol/L);
3.探索尿酸排泄相关指标(AeUR、CLUR、FEUA)、sUA动态变化曲线(AUC)、24小时尿酸排泄总量。
[Translation] Primary Objectives:
1. To evaluate the pharmacokinetic characteristics of a single oral dose of F-02-2-Na tablets in adult subjects;
2. To evaluate the safety of a single oral dose of F-02-2-Na tablets in adult subjects.
Secondary Objectives:
1. To evaluate the effect of food on the pharmacokinetic characteristics of F-02-2-Na tablets;
2. To evaluate the effects of a single oral dose of F-02-2-Na tablets in adult subjects: absolute value, percentage value, and target achievement rate (≤360 μmol/L);
3. To explore uric acid excretion-related indicators (AeUR, CLUR, FEUA), the dynamic change curve of sUA (AUC), and the total 24-hour uric acid excretion.
100 Clinical Results associated with F-02-2-Na
100 Translational Medicine associated with F-02-2-Na
100 Patents (Medical) associated with F-02-2-Na
100 Deals associated with F-02-2-Na