Tianjin Biochemical Pharmaceutical Co. Ltd.

Healthy subjects were used as test subjects, voriconazole for injection (0.2g) developed by Tianjin Lisheng Pharmaceutical Co., Ltd. was used as the test preparation, and voriconazole for injection (trade name: Weifan, specification: 0.2g) licensed by Pfizer Europe MA EEIG was used as the reference preparation; After single-dose and multiple-dose tests: 1) Compare the pharmacokinetic parameters of the test preparation and the reference preparation after single and multiple administrations; 2) Observe the safety of the test preparation and the reference preparation in Chinese healthy subjects. After bioequivalence test: 1) Evaluate the bioequivalence of the two preparations in Chinese healthy subjects; 2) Observe the safety of the test preparation and the reference preparation in Chinese healthy subjects.