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Last update 08 May 2025

Furunculous Myiasis

Last update 08 May 2025

Basic Info

Synonyms

Furuncular myiasis, Furuncular myiasis (disorder), Furunculoid myiasis

+ [2]

Introduction

Furuncular myiasis in humans is caused by two species: the Cayor worm (larvae of the African tumbu fly Cordylobia anthropophaga) and the larvae of the human botfly (Dermatobia hominis). In the case of Cordylobia anthropophaga, the females lay their eggs on damp fabric or on the ground. The larvae penetrate the skin following contact with the ground or with non-ironed contaminated fabric. Infection becomes evident within 10 to 15 days with the formation of a pseudo-furuncle or emergence of a maggot. Infestation is usually localised to the scalp of infected individuals.

Drugs associated with Furunculous Myiasis

Thymol-derived triazole

Target-

Mechanism-

Active Org.

Universidade Vila Velha

Originator Org.-

Active Indication

Furunculous Myiasis

Inactive Indication-

Drug Highest PhasePreclinical

First Approval Ctry. / Loc.-

First Approval Date20 Jan 1800

Clinical Trials associated with Furunculous Myiasis

CTR20232351

/ Not yet recruitingNot Applicable

健康受试者空腹和餐后状态下口服盐酸特比萘芬片的单中心、开放、随机、单剂量、两制剂、两周期、两序列、交叉生物等效性研究

[Translation] A single-center, open-label, randomized, single-dose, two-formulation, two-period, two-sequence, crossover bioequivalence study of oral terbinafine hydrochloride tablets in healthy subjects in the fasting and fed state

主要目的：以修正药业集团长春高新制药有限公司生产及提供的盐酸特比萘芬片（规格：0.25g）为受试制剂，按有关生物等效性试验的规定，与Novartis Farma- Produtos Farmacêeuticos,S.A. （葡萄牙文，持证商）的盐酸特比萘芬片【商品名】Lamisil®（Lamisil ®）（规格：0.25g）为参比制剂，进行生物等效性试验。次要目的：观察受试制剂盐酸特比萘芬片（规格：0.25g）与参比制剂盐酸特比萘芬片【商品名】Lamisil®（Lamisil ®），（规格：0.25g）在健康人群中的安全性。

[Translation]

Primary objective: To conduct bioequivalence study with Terbinafine Hydrochloride Tablets (Specification: 0.25g) produced and provided by Changchun High-Tech Pharmaceutical Co., Ltd. of Xiuzhen Pharmaceutical Group as the test preparation and Terbinafine Hydrochloride Tablets [Trade Name] Lamisil® (Lamisil ®) (Specification: 0.25g) of Novartis Farma- Produtos Farmacêeuticos, S.A. (Portuguese, licensed manufacturer) as the reference preparation. Secondary objective: To observe the safety of the test preparation Terbinafine Hydrochloride Tablets (Specification: 0.25g) and the reference preparation Terbinafine Hydrochloride Tablets [Trade Name] Lamisil® (Lamisil ®) (Specification: 0.25g) in healthy people.

Start Date-

Sponsor / Collaborator

Jilin Xiuzheng Medicine Group Changchun High-Newly Pharmaceuti

EUCTR2005-001573-10-ES

/ Not yet recruitingPhase 4

ESTUDIO DOBLE CIEGO CONTROLADO CON PLACEBO DE INMUNOTERAPIA CON UN EXTRACTO DE Dermatophagoides MEZCLA COMO TRATAMIENTO DEL ASMA PERSISTENTE LEVE-MODERADO Y SU PAPEL AHORRADOR DE MEDICACIÓN DE FONDO

Start Date22 Aug 2005

Sponsor / Collaborator-

100 Clinical Results associated with Furunculous Myiasis

100 Translational Medicine associated with Furunculous Myiasis

0 Patents (Medical) associated with Furunculous Myiasis

226

Literatures (Medical) associated with Furunculous Myiasis

17 Mar 2025·Journal of Medical Entomology

Myiasis by Cordylobia anthropophaga and C. rodhaini (Diptera: Calliphoridae) in Polish travelers to Africa with new molecular data

Article

Author: Sontag, Elżbieta ; Kuna, Anna ; Biernat, Beata ; Bykowska-Tumasz, Martyna ; Gładysz, Paweł ; Sulima, Małgorzata

AbstractMyiasis is a parasitic infestation of soft vertebrate tissues by larval stages of Diptera. We briefly described the lesion-causing genus Cordylobia Grünberg (Diptera: Calliphoridae). Three Polish travelers to Uganda, Gambia, and Senegal returned with furuncular myiasis. To identify the third-instar larvae removed from their skin, we examined the morphological features of the 3 specimens and sequenced a 5’ barcoding fragment of the cytochrome c oxidase subunit I gene (COI-5P). One larva was identified as C. rodhaini Gedoelst, and 2 larvae were identified as C. anthropophaga (Blanchard). We were the first to submit the COI-5P of C. rodhaini to GenBank and the Barcode of Life Database. This is the first record of the importation of C. anthropophaga and the second record of the importation of C. rodhaini to Poland.

01 Mar 2025·Pediatric Dermatology

Furcuncular Myiasis of the Scalp Caused by Chrysomya bezziana

Article

Author: Gaurav, Vishal ; Tyagi, Mehul ; Das, Shukla ; Pandhi, Deepika

ABSTRACTWe report a rare case of furuncular myiasis in a 7‐year‐old boy presenting with a discharging nodule over the scalp. The report details the clinical presentation, examination findings, and dermoscopic features of furuncular myiasis. To the best of our knowledge, Chrysomya bezziana has never been reported to cause furuncular myiasis. In vivo and ex vivo dermoscopy features help in diagnosis by obviating the need for microscopy.

18 Jan 2025·Cureus

When Artificial Intelligence (AI) Met a Botfly: The First AI-Assisted Diagnosis of Cutaneous Furuncular Myiasis in a Community-Based Surgical Practice

Article

Author: Santos, David ; Maurice, Joseph P

In this report, we describe a rare case of a parasitic infection of Dermatobia hominis in a patient who presented to a general otolaryngology clinic in a Seattle suburb. The 69-year-old male patient initially presented with a unique furuncle on his scalp after returning from a vacation in Belize. Initially unrecognized as a cutaneous manifestation of D. hominis larva, the patient was brought for surgical excision and biopsy of the lesion to a community-based surgical center. This case highlights how artificial intelligence (AI) was innovatively utilized intraoperatively to assist the surgeon in confirming the diagnosis of this rare infection and facilitating treatment. AI has rapidly become an important tool used by physicians worldwide and is evolving in its applications in healthcare. AI-assisted image analysis has recently been demonstrated to be effective in assisting in the diagnosis and treatment of skin conditions including cancers and rare parasitic conditions such as leishmaniasis. A review of the literature reveals that our report is a first on AI-assisted intraoperative diagnosis of D. hominis. We discuss this case, the differential diagnosis, treatment options, and innovative use of ubiquitous AI in the operating room to efficiently assist clinicians in confirming their suspicions and ensuring appropriate treatment.

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Furunculous Myiasis

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