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Last update 28 May 2025
TQB-2618
Last update 28 May 2025
Overview
Basic Info
Drug Type Monoclonal antibody |
Synonyms TQB 2618, TQB2618 |
Target |
Action inhibitors |
Mechanism TIM3 inhibitors(Hepatitis A virus cellular receptor 2 inhibitors) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
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Related
16
Clinical Trials associated with TQB-2618NCT06010901
A Phase Ib Clinical Study to Evaluate the Efficacy and Safety of of TQB2618 Injection Monotherapy and Combination Regimen (With Penpulimab Injection ±Anlotinib Hydrochloride Capsules) in the Four or Later Lines of Treatment of Advanced Colorectal Cancer.
CTR20233217
评估 TQB2618 注射液单药及联合方案（派安普利单抗±安罗替尼）四线及后线治疗晚期结直肠癌的有效性和安全性 Ib 期临床研究
[Translation] Phase Ib clinical study to evaluate the efficacy and safety of TQB2618 injection alone and in combination with penpulimab ± anlotinib in the fourth-line and later-line treatment of advanced colorectal cancer
NCT05975645
A Phase Ib Clinical Study to Evaluate the Efficacy and Safety of TQB2618 Injection Combined With Penpulimab Injection and Anlotinib Hydrochloride Capsules as First-line Treatment for Advanced Hepatocellular Carcinoma.
100 Clinical Results associated with TQB-2618
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100 Translational Medicine associated with TQB-2618
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100 Patents (Medical) associated with TQB-2618
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100 Deals associated with TQB-2618
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Esophageal Squamous Cell Carcinoma | Phase 2 | China | 26 May 2023 | |
| Recurrent Squamous Cell Carcinoma of the Head and Neck | Phase 2 | China | 23 May 2023 | |
| Squamous cell carcinoma, metastatic | Phase 2 | China | 23 May 2023 | |
| Nasopharyngeal Carcinoma | Phase 2 | China | 27 Oct 2022 | |
| Recurrent Lymphoma | Phase 2 | China | 09 Jun 2022 | |
| Refractory Lymphoma | Phase 2 | China | 09 Jun 2022 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 28 Apr 2022 | |
| Squamous cell carcinoma of head and neck metastatic | Phase 1 | China | 14 Mar 2024 | |
| Advanced Colorectal Adenocarcinoma | Phase 1 | China | 13 Jan 2024 | |
| Metastatic Colorectal Carcinoma | Phase 1 | China | 22 Dec 2023 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 2 | 17 | rgfcjczjfh(mhruqyubrx) = cjqyrxoblt koufxmclly (pgyncnqpmc ) View more | Negative | 12 Dec 2024 | |||
WCLC2024 Manual  | Phase 1 | 93 | btzddyxwcu(evbkotewzz) = bmwhprajfg zzpwyjisom (qnndisdlnj ) View more | Positive | 10 Sep 2024 | ||
btzddyxwcu(evbkotewzz) = bsiajqbjug zzpwyjisom (qnndisdlnj ) View more | |||||||
NCT05400876 (EHA2024) Manual | Phase 1 | 21 | xbxzcriosm(zyajhzekke) = 17 (81%) patients experienced treatment-related adverse events (TRAEs), 5 (23.8%) of whom experienced grade 3 or above TRAEs. The most frequent TRAEs (≥15%) were platelet count decreased (23.8%), anemia (23.8%), alanine aminotransferase increased (19%) and Aspartate aminotransferase increased (19%). The most common grade 3 or above TRAEs were anemia (9.5%) and white blood count decreased (9.5%). xwobbmpkyh (rierozqirr ) View more | Positive | 14 May 2024 |
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