The objective is to estimate the efficacy of tinidazole for the treatment of Mycoplasma genitalium (MG) among male patients who have been diagnosed with non-gonococcal urethritis (NGU) at the Public Health - Seattle &King County (PHSKC) Sexual Health Clinic (SHC). Tinidazole was approved by the Food and Drug Administration (FDA) in May 2004 to treat other infections (i.e., trichomoniasis, giardiasis, amebiasis, bacterial vaginosis) but has not been systematically tested for effectiveness against M. genitalium. The dosing that the investigators are proposing does not significantly increase the risk associated with taking tinidazole and this investigation meets criteria for an IND exemption.

Start Date23 Jul 2025

Sponsor / Collaborator

University of Washington

[+1]

ChiCTR2500097338

/ Not yet recruitingNot ApplicableIIT

A large-scale population study on the eradication effect of Helicobacter pylori

Start Date01 Nov 2024

Sponsor / Collaborator

Fujian Medical University

100 Clinical Results associated with Tinidazole

100 Translational Medicine associated with Tinidazole

100 Patents (Medical) associated with Tinidazole

1,840

Literatures (Medical) associated with Tinidazole

01 Feb 2026·VETERINARY RESEARCH COMMUNICATIONS

First report of Tritrichomonas foetus in cats from Northeastern Brazil

Article

Author: Dos Santos Silva, Samara ; Ramos, Rafael Antonio Nascimento ; Medeiros, Anderson Eduardo Correia ; Mendes-Marques, Carina Lucena ; Alves, Leucio Câmara ; de Lara Oliveira Lima, Maria ; de Araújo, Bruno Vinicios Silva ; de Melo, Renata Pimentel Bandeira

Tritrichomonas foetus is a protozoan parasite implicated in intestinal infections in domestic cats, frequently associated with chronic diarrhea. Although reported on nearly all continents, its occurrence in Brazil is rare and has been restricted to the Southeast region so far. This study reports, for the first time, T. foetus infection in two Maine Coon cats originating from the Northeastern region of the country. Both animals exhibited persistent diarrhea unresponsive to initial therapeutic interventions and underwent clinical and laboratory evaluation. Fecal analysis performed on samples obtained by colonic lavage revealed motile trophozoites exhibiting morphological features consistent with T. foetus. Molecular confirmation was achieved through PCR amplification and subsequent sequencing, with sequences deposited under accession numbers PV857727 and PV857728. BLAST analysis demonstrated 100% nucleotide identity with reference sequences available in GenBank. Following diagnosis, both cats received appropriate treatment with Tinidazole (Drogavet, Brazil) at a dose of 30 mg/kg, administered every 24 h for 14 days, resulting in complete clinical remission and subsequent negative fecal examinations. These findings expand current knowledge on the geographical distribution of feline trichomonosis in Brazil, highlight the diagnostic challenges of T. foetus infection, and reinforce the importance of including this protozoan in the differential diagnosis of feline enteropathies.

01 Jan 2026·Journal of Oleo Science

In vitro Anti-<i>Trichomonas vaginalis</i> Activity of Cyprus Endemic Plant <i>Origanum majorana</i> Essential Oil and Synergistic Effect with Metronidazole

Article

Author: Hanoğlu, Azmi ; Özel, Yener ; Süer, Kaya ; Ünlü, Mehmet ; Çavuş, İbrahim ; Başer, K. Hüsnü Can ; Özbilgin, Ahmet ; Şanlıdağ, Tamer ; Güler, Emrah

Currently, the treatment of Trichomonas vaginalis (T. vaginalis) typically involves the use of 5-nitroimidazoles (such as metronidazole and tinidazole). However, an increasing failure in treatment is observed due to resistance developed to these drugs. For this reason, alternative drugs have been investigated, especially by using natural products. In our study, the anti-T. vaginalis activity of the Origanum majorana essential oil (OMEO), which is a Cyprus endemic plant, and its synergistic effect with metronidazole were investigated. The essential oil was extracted through hydrodistillation of the dried flowering tops of the plant. Gas chromatography and mass spectrometry (GC-MS) analyses were performed using the Agilent 5975 GC-MSD system. L929 mouse fibroblast cell line was used to determine cytotoxic activity. Two clinical strains and one metronidazole-resistant T. vaginalis standard strain were used. LC₅₀, and MLC (minimum lethal concentration) values of OMEO and metronidazole were determined by the broth microdilution method in vitro in aerobic and anaerobic conditions. The combination of OMEO with metronidazole was investigated against all strains by the checkerboard method. The major compounds in the OMEO content were determined as cis-sabinene hydrate (29.1%) and terpinen-4-ol (19.6%). In cytotoxic analyses, it was observed that the cell viability remained stable at low doses. OMEO is effective against all three T. vaginalis strains. There is a significant difference between the IC₅₀ averages at the 24^th and 48^th hours (333.03 µg/mL and 226.43 µg/mL, respectively) in aerobic conditions (p=0.003). In addition, there is a statistically significant relationship between the results of the 24^th and 48^th hours (348.77 µg/mL and 238.80 µg/mL, respectively) in the anaerobic conditions (p=<0.0001). In general, OMEO has been shown to have a synergistic effect with metronidazole. In conclusion, we believe that OMEO is a potential natural agent that can be particularly used in the treatment of protozoan infections, including T. vaginalis.

01 Jan 2026·AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Doxycycline vs levofloxacin combined with tinidazole for treating chronic endometritis: a randomized controlled trial

Article

Author: Yue Liu ; Xiao You ; Dacheng Qu ; Zijun Zhao ; Xiaorui Jiang

BACKGROUND:

The spontaneous cure rate of chronic endometritis is very low, and doxycycline alone or a combination of levofloxacin and tinidazole are the 2 most widely used antibiotic regimens for treating chronic endometritis. However, there is currently no consensus regarding the optimal antibiotic regimen.

OBJECTIVE:

This study aimed to assess the effectiveness and safety of doxycycline alone and levofloxacin combined with tinidazole as antibiotic therapies for chronic endometritis.

STUDY DESIGN:

In this parallel randomized controlled trial comparing 2 antibiotic therapies for chronic endometritis, 172 patients with chronic endometritis diagnosed using CD138 were randomly divided into treatment and control groups. Levofloxacin combined with tinidazole was administered to the treatment group, whereas doxycycline alone was administered to the control group. Repeated hysteroscopy and endometrial biopsies were performed during the first menstrual proliferative period after antibiotic therapy to evaluate the resolution of chronic endometritis. The one-course cure rate for chronic endometritis, based on the conversion of CD138 expression from positive to negative, and the incidence of adverse reactions were compared between the groups.

RESULTS:

A total of 160 patients were enrolled, with 79 in the treatment group and 81 in the control group. After one course of antibiotic therapy, there was no difference in the chronic endometritis cure rate between the groups (84.8% vs 77.8%) (P=.255). In the subgroup analysis based on chronic endometritis severity, there were no differences between the groups regardless of whether chronic endometritis was mild (88.9% vs 83.7%) (P=.464) or severe (79.4% vs 68.8%) (P=.322). In the intent-to-treat analysis (n=172), the cure rates were 77.9% (67/86) and 73.3% (63/86) in the treatment and control groups, respectively, showing no difference between the groups (P=.595). The incidence of adverse reactions was significantly higher in the treatment group (11.6% vs 2.3%, P=.032) in the safety analysis.

CONCLUSION:

The 2 antibiotic therapy regimens were effective and safe for treating chronic endometritis. The study did not find a statistically marked difference in cure rate between the 2 antibiotic therapy groups. Doxycycline alone is recommended as the first-line treatment because of the lower incidence of adverse reactions.

News (Medical) associated with Tinidazole

03 Dec 2025

·pharma.economictimes.indiatimes.com

Par panel flags steep divergence in Drug Pricing; calls to review Trade margins

New Delhi: The Parliamentary Standing Committee on chemicals and fertilizers has flagged a ‘whopping difference’ between the prices at which drugs are sold to stockists and the prices charged to end-consumers, i.e., patients. The committee in its 14th report analyzing the impact of prise rise of medicines stated that many commonly prescribed medicines for everyday and chronic ailments are being sold at excessively high prices, with "unjustified trade margins" ranging from “600 per cent to 1100 per cent” over the price charged from stockist (PTS). Citing cases such as Ibrufen –anit-inflamaotry drug and Labocof – drug for cough and cold, the report suggest their the final market price is Rs. 4,560 and Rs. 2,850 respectively, however the the price charged from the stockists are Rs. 831 and Rs. 316, resulting in a steep difference of Rs. 3,729 and Rs. 2,534. Similarly, for Ciprofloxacin 500 mg and Tinidazole 600 mg—a common antibiotic FDC—the report notes that the medicine is supplied to stockists at a PTS of Rs 450, while its retail price is Rs. 3,500, reflecting a whopping difference of Rs. 3,050 The price to stockist refers to the amount charged by the drug marketer, while the Maximum Retail Price (MRP) is the amount paid by consumers. The MRP is determined after adding the margins of stockists, distributors and retailers, excluding taxes. According to the committee for drugs that fall under the non-scheduled and FDC category the steep divergence in the drugs initial and final prices is linked with a "loophole" in the country’s price control norms as the Drugs (Prices Control) Order of 2013 lacks control on trade margins, leavong room for widespread profiteering at the cost of patients. Secondly, under the present framework the price to stockist (PTS) data also remains undisclosed to the public, and fails to reveal the true extent of profiteering, it added. Presently, for non-scheduled formulations companies are permitted to increase the MRP of each product by up to 10 per cent annually, however as per the committee report, the absence of initial price fixation makes this control “largely meaningless and allows manufacturers to launch non-scheduled formulations, both branded and generic, at arbitrary points.” The Department of Pharmaceuticals (DoP) in its response when questioned about the wide gap between supplier prices and MRPs, cited distribution costs, which the committee has termed as unconvincing and has suggested to undertake a comprehensive review of the extant price regulation framework to plug the existing loopholes in the pricing mechanism. Seeking more clarity on the drug pricing and trade margins across the distribution chain, the committee recommended a DoP-led study to ascertain the factors driving the steep price hikes between the PTS and MRP. Meanwhile, in the absence of ceilings on trade margins it has also asked the drug price controller National Pharmaceutical Pricing Authority (NPPA), “to consider some appropriate control over prices of common non-scheduled formulations to obviate scope for abuse by manufacturers and marketers.” By Abhijeet Singh ,

03 Dec 2025

·pharma.economictimes.indiatimes.com

Par panel flags steep divergence in Drug Pricing; calls to review Trade margins

23 Aug 2024

·pharma.economictimes.indiatimes.com

Govt bans 156 medicines including antibiotics, painkillers, multivitamins: Here is the full list

New Delhi: In a significant move aimed at safeguarding public health, the Indian government has banned 156 fixed-dose combination (FDC) drugs, including a variety of antibiotics, painkillers, multivitamins, and medications for treating fever and hypertension. This decision marks the largest crackdown on FDCs since 2016, when 344 such drugs were prohibited. The Union Ministry of Health and Family Welfare issued a gazette notification on Thursday, officially prohibiting the manufacture, sale, and distribution of the banned FDCs. The ban was based on the recommendations of an expert panel that reviewed a total of 324 FDCs. Impact on Pharmaceutical Industry The banned FDCs include popular combinations such as mefenamic acid and paracetamol injections, commonly used for pain relief and fever, and omeprazole magnesium with dicyclomine HCl, used to treat abdominal pain. The ban is expected to impact major pharmaceutical companies, including Sun Pharmaceuticals, Cipla, Dr. Reddy's Laboratories, Torrent Pharmaceuticals, and Alkem Laboratories. Fixed Dose Combinations Drug Banned List Here is a table listing all 156 banned Fixed Dose Combinations (FDCs) SN Fixed Dose Combination (FDC) 1 Amylase + Protease + Glucoamylase + Pectinase + Alpha Galactosidase + Lactase + Beta-Gluconase + Cellulase + Lipase + Bromelain + Xylanase + Hemicellulase + Malt diastase + Invertase + Papain 2 Antimony Potassium Tartrate + Dried Ferrous Sulphate 3 Benfotiamine + Silymarin + L-Ornithine L-aspartate + Sodium Selenite + Folic acid + Pyridoxine hydrochloride 4 Bismuth Ammonium Citrate + Papain 5 Cyproheptadine HCl + Thiamine HCl + Riboflavine + Pyridoxine HCl + Niacinamide 6 Cyproheptadine Hydrochloride + Tricholine Citrate + Thiamine Hydrochloride + Riboflavine + Pyridoxine Hydrochloride 7 Rabeprazole Sodium (As enteric coated tablet) + Clidinium Bromide + Dicyclomine HCl + Chlordiazepoxide 8 Fungal Diastase + Papain + Nux vomica Tincture + Cardamom Tincture + Casein Hydrolysed + Alcohol 9 Mefenamic Acid + Paracetamol Injection 10 Omeprazole Magnesium + Dicyclomine HCl 11 S-adenosyl methionine + Metadoxine + Ursodeoxycholicacid BP + L-Methylfolate Calcium eq. to L- Methylfolate + Choline bitartratee + Silymarin + L-ornithine Laspartate + Inositol + Taurine 12 Silymarin + Thiamine Mononitrate + Riboflavin + Pyridoxine HCl + Niacinamide + Calcium pantothenate + Vitamin B12 13 Silymarin + Pyridoxine HCl + Cyanocobalamin + Niacinamide + Folic Acid 14 Silymarin + Vitamin B6 + Vitamin B12 + Niacinamide + Folic acid + Tricholine Citrate 15 Sodium Citrate + Citric Acid Monohydrate Flavored with Cardamom Oil, Caraway Oil, Cinnamon Oil, Clove Oil, Ginger Oil + Alcohol 16 Sucralfate + Acelofenac 17 Sucralfate + Domperidone + Dimethicone 18 Sucralfate + Domperidone 19 Tincture Ipecacuanha + Tincture Urgenia + Camphorated Opium Tincture + Aromatic Spirit of Ammonia + Chloroform + Alcohol 20 Ursodeoxycholic Acid + Metformin HCl 21 Weak Ginger tincture + Aromatic Spirit of Ammonia + Peppermint Spirit + Chloroform + Sodium Bicarbonate + Compound Cardamom + Alcohol 22 Sucralfate + Pantoprazole Sodium + Zinc Gluconate + Light Magnesium Carbonate 23 Aloe + Vitamin E Soap 24 Povidone Iodine+ Metronidazole + Aloe 25 Azelaic acid + Tea Tree Oil + Salicylic acid + Allantoin + Zinc oxide + Aloe vera + Jojoba oil + Vitamin E + Soap noodles 26 Azithromycin + Adapalene 27 Calamine + Aloes + Allantoin 28 Calamine + Diphenhydramine Hydrochloride + Aloe + Glycerine + Camphor 29 Chlorphenesin + Zinc oxide + Starch 30 Clindamycin Phosphate + Zinc acetate 31 Gamma Benzene Hexachloride + Benzocaine 32 Glucosamine hydrochloride + Diacerein + Menthol + Camphor + Capsaicin 33 Hydroxyquinone 2.0%w/w + Octyl Methoxycinnamate 5.0% w/w + Oxybenzone 30 % w/w 34 Ketoconazole +Zinc Pyrithione +D-Panthenol +Tea Tree Oil +Aloes 35 Ketoconazole +Aloe vera+ Vitamin A Acetate 36 Ketoconazole +Aloes + ZPTO 37 Kojic Acid +Arbutin +Octinoxate +Vitamin E + Mulberry 38 Lornoxicam +capsaicin +menthol+ camphor 39 Lornoxicam + Thiocolchicoside +Oleum Lini +Menthol + Methyl salicylate 40 Menthol + Aloe vera Topical Spray 41 Menthol +Lignocaine HCl +Aloe vera gel +Clotrimazole +Diphenhydramine 42 Miconazole nitrate + Gentamicin + Fluocinolone Acetonide +Zinc Sulphate 43 Miconazole +Tinidazole 44 Minoxidil +Aminexil+ Alcohol 45 Minoxidil +Azelaic acid + saw palmetto 46 Minoxidil +Aminexil 47 Pine Bark extract+ Kojic acid +Sodium Ascorbyl Phosphate 48 Povidone Iodine +Tinidazole +Zinc sulphate 49 Povidone Iodine + Ornidazole + Dexpanthenol 50 Salicyclic acid +Aloe vera+ Allantoin +D-Panthenol 51 Silver sulphadiazine +Chlorhexidine Gluconate solution +Allantoin + Aloe vera gel +Vitamin E acetate 52 Sodium salicylate + Zinc gluconate + Pyridoxine HCl 53 Tetracycline + Colistin Sulphate 54 Clomiphene +Ubidecarenone 55 Combikit of Clomiphene Citrate + Estradiol Valerate 56 Flavoxate HCl +Ofloxacin 57 Clomiphene Citrate +N-Acetylcysteine 58 Primerose Oil +Cod liver oil 59 Sildenafil Citrate +Papaverine +L-Arginine 60 Tranexamic acid +Mefenamic acid + Vitamin K1 61 Divalproex Sodium +Oxcarbazepine 62 Divalproex Sodium + Levetiracitam 63 Ergotamine tartrate +Caffeine + Paracetamol +Prochlorperazine maleate 64 Piracetam + Ginkgo biloba extracts + Vinpocetin 65 Ginkgo biloba + methylcobalamin 66 Ginkgo biloba + methylcobalamin + Alpha lipoic acid +Pyridoxine HCl 67 Ginseng Extract +Dried extract of Ginkgo Biloba 68 Meclizine HCl+ Paracetamol + Caffeine 69 Nicergoline + Vinpocetine 70 Gamma Linolenic Acid + Methylcobalamin 71 Beclomethasone Dipropionate + Neomycin Sulphate + Clotrimazole + Lignocaine HCl 72 Boric acid+ Phenylephrine HCl + Naphazoline Nitrate + Menthol + Camphor 73 Naphazoline HCl + Chlorpheniramine Maleate + Zinc Sulphate + Hydroxy Propyl Methyl Cellulose 74 Chlorpheniramine Maleate + Naphazoline HCl + Zinc Sulphate + Sodium Chloride + Hydroxy Propyl Methyl Cellulose 75 Chlorpheniramine Maleate + Naphazoline HCl + Hydroxy Propyl Methyl Cellulose 76 Chlorpheniramine Maleate + Sodium Chloride + Boric Acid + Tetrahydrozoline HCl 77 Chlorpheniramine Maleate + Phenylephrine HCl + Antipyrine 78 Ketorolac Tromethamine + Chlorpheniramine Maleate + Phenylephrine HCl + Hydroxy Propyl Methyl Cellulose 79 Ketorolac Tromethamine + Flurometholone 80 Naphazoline HCl + Zinc Sulphate + Boric Acid + Sodium Chloride+ Chlorpheniramine Maleate 81 Naphazoline HCl + Hydroxy Propyl Methyl Cellulose + Boric Acid + Borax + Menthol + Camphor 82 Naphazoline HCl + Hydroxy Propyl Methyl Cellulose + Chlorpheniramine Maleate SN Fixed Dose Combination (FDC) 83 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Menthol + Camphor 84 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Sodium Chloride + Hydroxy Propyl Methyl Cellulose 85 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Sodium Chloride + Methylparaben 86 Methenamine + Sodium Benzoate + Benzyl Alcohol 87 Paracetamol + Phenylephrine Hydrochloride + Chlorpheniramine Maleate 88 Paracetamol + Phenylephrine Hydrochloride + Chlorpheniramine Maleate + Caffeine 89 Propoxyphene + Chlorpheniramine Maleate 90 Propoxyphene + Phenylephrine Hydrochloride + Chlorpheniramine Maleate 91 Propoxyphene + Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride 92 Sodium Benzoate + Sodium Citrate + Citric Acid 93 Vitamin A Palmitate + Vitamin C + Vitamin E + Vitamin B6 + Vitamin B12 94 Vitamin A Palmitate + Vitamin C + Vitamin E + Niacinamide 95 Vitamin B6 + Vitamin B12 + Vitamin C 96 Vitamin B6 + Vitamin B12 + Niacinamide 97 Vitamin B12 + Vitamin B6 + Vitamin C + Folic Acid 98 Vitamin B12 + Vitamin B6 + Niacinamide + Folic Acid 99 Vitamin C + Vitamin E + Vitamin A + Niacinamide 100 Vitamin D + Calcium + Magnesium 101 Vitamin D + Calcium + Magnesium + Zinc 102 Calcium + Vitamin D + Vitamin K 103 Calcium + Vitamin D + Magnesium + Zinc 104 Calcium + Vitamin D + Vitamin K + Magnesium 105 Calcium + Vitamin D + Vitamin K + Magnesium + Zinc 106 Vitamin E + Vitamin A + Vitamin C + Niacinamide 107 Vitamin E + Vitamin A + Vitamin C + Folic Acid 108 Vitamin E + Vitamin A + Vitamin C + Biotin 109 Vitamin E + Vitamin A + Vitamin C + Vitamin B12 110 Vitamin E + Vitamin C + Folic Acid 111 Vitamin E + Vitamin C + Biotin 112 Vitamin E + Vitamin C + Vitamin B12 113 Vitamin E + Vitamin C + Zinc 114 Calcium + Vitamin D + Omega-3 Fatty Acids 115 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K 116 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K + Magnesium 117 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K + Zinc 118 Vitamin A + Vitamin C + Vitamin E + Beta-Carotene 119 Vitamin A + Vitamin C + Vitamin E + Beta-Carotene + Zinc 120 Vitamin C + Vitamin E + Beta-Carotene 121 Vitamin C + Vitamin E + Beta-Carotene + Zinc 122 Vitamin C + Vitamin E + Selenium 123 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids 124 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Magnesium 125 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Zinc 126 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Biotin 127 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Selenium 128 Vitamin E + Vitamin A + Vitamin C + Zinc 129 Vitamin E + Vitamin A + Vitamin C + Selenium 130 Vitamin E + Vitamin A + Vitamin C + Biotin 131 Vitamin E + Vitamin A + Vitamin C + Folic Acid + Niacinamide 132 Vitamin E + Vitamin C + Beta-Carotene + Zinc 133 Vitamin C + Vitamin E + Biotin + Folic Acid 134 Vitamin C + Vitamin E + Beta-Carotene + Folic Acid 135 Vitamin C + Vitamin E + Beta-Carotene + Selenium 136 Vitamin E + Vitamin C + Beta-Carotene + Biotin 137 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Biotin 138 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Selenium 139 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Vitamin B12 140 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Vitamin B6 141 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Folate 142 Calcium + Vitamin D + Magnesium + Vitamin K + Omega-3 Fatty Acids 143 Calcium + Vitamin D + Magnesium + Vitamin K + Biotin 144 Calcium + Vitamin D + Magnesium + Vitamin K + Selenium 145 Calcium + Vitamin D + Magnesium + Vitamin K + Vitamin B12 146 Calcium + Vitamin D + Magnesium + Vitamin K + Folate 147 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Vitamin B6 148 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Vitamin B12 149 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Folic Acid 150 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Biotin 151 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Selenium 152 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids 153 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Zinc 154 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Biotin 155 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Selenium 156 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Vitamin B12

Drug Approval

100 Deals associated with Tinidazole

External Link

KEGG	Wiki	ATC	Drug Bank
D01426	Tinidazole	P01AB02 J01XD02	DB00911

R&D Status

Approved

10 top approved records.

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Indication	Country/Location	Organization	Date
Bacterial Vaginosis	United States	Mission Pharmacal Co.	21 May 2007
Amebiasis	United States	Mission Pharmacal Co.	17 May 2004
Giardiasis	United States	Mission Pharmacal Co.	17 May 2004
Trichomonas Infections	United States	Mission Pharmacal Co.	17 May 2004
Bacterial Infections	China	Zhejiang Sukean Pharmaceutical Co Ltd.	01 Jan 1994

Developing

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Mycoplasma genitalium infection	Phase 2	United States	Hologic, Inc.	23 Jul 2025
non-gonococcal urethritis (NGU)	Phase 2	United States	Hologic, Inc.	23 Jul 2025

Clinical Result

Indication

Phase

Evaluation

View All Results

Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT01481844 (Pubmed \| J Biol Chem \| PLoS One) Manual	Phase 3	Helicobacter pylori infection Second line	101	Lansoprazole+Amoxicillin Trihydrate+Clarithromycin+Tinidazole	dnjwpnoqyy(ssfysrcszo) = pfjscrbhce kgqewpyfuk (vyozrlwroo )	Positive	28 Sep 2017
				Lansoprazole+Bismuth Subsalicylate+Metronidazole+Tetracycline Hydrochloride	dnjwpnoqyy(ssfysrcszo) = zyhpkhxuns kgqewpyfuk (vyozrlwroo )
Pubmed \| Indian J Pharmacol	Not Applicable	Bacterial Vaginosis	344	Metronidazole (2 g)	ebmghmpuyq(vmohoyodrz) = kuiofhtlzf miqogiffjt (utjpgordfy )	Positive	01 Mar 2012
				Tinidazole (2 g)	ebmghmpuyq(vmohoyodrz) = qkpusqhopk miqogiffjt (utjpgordfy )
NCT00334633 (CTgov)	Phase 4	Bacterial Vaginosis	593	tinidazole+metronidazole (Tinidazole 1 gm)	tqujmviyac = fjothgbmpa mxfrehpkaj (vkicoefftr, wfbxbkbvlv - zfhgrolzro) View more	-	23 Jun 2011
				tinidazole+metronidazole (Control)	geqitwxgrz = kyfzfdlsyj cbvocnembf (nupnqlfveb, foiiqczjju - jotfsilkqn)
NCT00229216 (Pubmed \| Obstet Gynecol)	Phase 3	Bacterial Vaginosis	235	Tinidazole 1 g once daily for 5 days	fqjmodqbuc(djnhqlqnoh) = bixdirhidg kckwxigrtu (pzibrszzgk )	-	01 Aug 2007
				Tinidazole 2 g once daily for 2 days	fqjmodqbuc(djnhqlqnoh) = ecgmljxtgy kckwxigrtu (pzibrszzgk )
NCT00313131 (Pubmed \| Bull World Health Organ)	Phase 3	Vaginal Discharge	1,570	Single-dose tinidazole plus fluconazole (TF)	qsrhxqupqf(psdmjuprho) = zpfoykupgy kbfjcnrqjp (ivdtfjvpxw ) View more	Positive	01 Sep 2006
				Treatment for 7 days with metronidazole plus 3 days of treatment with vaginal clotrimazole (MC)	qsrhxqupqf(psdmjuprho) = fkxlcaojgf kbfjcnrqjp (ivdtfjvpxw ) View more

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