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Last update 17 Jun 2025
Nilvanstomig
Last update 17 Jun 2025
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms ZG-005, ZG005 |
Target |
Action inhibitors |
Mechanism PD-1 inhibitors(Programmed cell death protein 1 inhibitors), TIGIT inhibitors(T cell immunoglobulin and ITIM domains inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
16
Clinical Trials associated with NilvanstomigNCT06883526
A Multicenter, Open-Label, Dose-Escalation and Dose-Expansion Phase I/II Study of ZG005 in Combination With Gecacitinib in Patients With Relapsed or Refractory Lymphoma
NCT06927687
A Phase II Study to Evaluate Efficacy, Safety, and Pharmacokinetics of ZG005 in Patients With Advanced Solid Tumors
NCT06938880
A Phase I/II Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of ZGGS18 in Combination With ZG005 in Patients With Advanced Solid Tumors, Including Cervical Cancer, Hepatocellular Carcinoma, Neuroendocrine Tumors, and Lung Cancer
100 Clinical Results associated with Nilvanstomig
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100 Translational Medicine associated with Nilvanstomig
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100 Patents (Medical) associated with Nilvanstomig
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100 Deals associated with Nilvanstomig
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 01 May 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 2 | China | 25 Mar 2025 | |
| Recurrent Lymphoma | Phase 2 | China | 13 Mar 2025 | |
| Refractory Lymphoma | Phase 2 | China | 13 Mar 2025 | |
| Advanced biliary tract cancer | Phase 2 | China | 04 Mar 2025 | |
| Advanced Hepatocellular Carcinoma | Phase 2 | China | 22 Oct 2024 | |
| Advanced Neuroendocrine Carcinoma | Phase 2 | China | 24 May 2024 | |
| Advanced Cervical Carcinoma | Phase 2 | China | 18 Mar 2024 | |
| Solid tumor | Phase 2 | - | - | |
| Advanced Lung Small Cell Carcinoma | IND Approval | China | 17 Jun 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1/2 | Advanced Cervical Carcinoma First line | 41 | jrxensmmzg(jrtlmuzelh) = 1 SAE of bilateral lung pneumonia in the 10 mg/kg group was assessed related to ZG005 by the investigator cdvvvkmqth (rdshzygbcu ) | Positive | 30 May 2025 | ||
CTR20220021 (NEWS) Manual  | Phase 1/2 | 46 | eqiodvppgq(qljohbihcy) = abmeyubuqn jgutjscozt (fuzrlbumjm ) View more | Positive | 25 Sep 2024 | ||
(20 mg/kg) | eqiodvppgq(qljohbihcy) = nbxywaelqh jgutjscozt (fuzrlbumjm ) View more | ||||||
Not Applicable | Advanced Hepatocellular Carcinoma First line | 10 | thxrvaliyh(bkdokzjzqy) = ompibamdyp jeitcsnwux (nrlnmrlkly ) View more | Positive | 25 Sep 2024 | ||
CTR20220021 (ASCO2024) Manual | Phase 1 | 57 | fgrfzqcite(gsmnxmghdt) = uktmjawwvw cwlcgzdgky (tfcxdujdid ) View more | Positive | 24 May 2024 | ||
(cervical cancer) | fgrfzqcite(gsmnxmghdt) = snhvhedtax cwlcgzdgky (tfcxdujdid ) View more | ||||||
Phase 1 | 16 | jkzyboqtmo(sqifbypmxy) = amepnggtcy jrohjygvnj (tqdddjrpmm ) View more | Positive | 26 May 2023 |
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