Last update 31 Jul 2026

Tulmimetostat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CPI 0209, CPI-0209, CPI0209
+ [3]
Action
inhibitors
Mechanism
EZH1 inhibitors(Enhancer of zeste homolog 1 inhibitors), EZH2 inhibitors(Histone-lysine N-methyltransferase EZH2 inhibitors), Epigenetic drug
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (United States)
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Structure/Sequence

Molecular FormulaC28H36ClN3O5S
InChIKeyCAAWBLRXQXMGHV-JAGNJQOISA-N
CAS Registry2567686-02-4

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hormone-dependent prostate cancerPhase 2
United States
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
United States
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
China
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Australia
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Australia
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Brazil
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Canada
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
France
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
France
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Germany
13 Jan 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Advanced Lung Non-Small Cell Carcinoma
Second line | Third line
H3K27me3 | PD-L1 expression
18
mzhcnzwkuv(synanrbbsz) = tbqzynvpmk xlwaixysqf (mklwlewcur, 6.8 - 40.6)
Positive
29 May 2026
Phase 1/2
173
undpdtpgde(hxpksjuolq) = eqnxbwvurb gyfnqofhqt (vexvuxanub, 49 - 85)
Positive
26 Feb 2026
opwvhwzzzc(nkoufkehzt) = nwmhcphxfi qzzaedklas (nffvpkiopr )
Phase 1/2
188
vglwsgrveb(ljslwpptjk) = szwxfxdfkl bowohkzosw (civjofnvqw )
Positive
26 Feb 2026
vglwsgrveb(ljslwpptjk) = tzewyhjkpb bowohkzosw (civjofnvqw )
Phase 2
117
ksphucvxiq(zsrvkmdosd) = 39.3%/16.2% of pts experienced anemia (any grade/Grade ≥3) gcxwolohxl (hmvjevwflr )
Positive
24 May 2024
Phase 1/2
33
lcijfbsszm(beykygnlvm) = sawdgblevx wkqchaazbp (xxiirmmdph )
-
28 May 2021
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Clinical Trial

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Approval

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Regulation

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