Last update 03 Jun 2026

Tulmimetostat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CPI 0209, CPI-0209, CPI0209
+ [3]
Action
inhibitors
Mechanism
EZH1 inhibitors(Enhancer of zeste homolog 1 inhibitors), EZH2 inhibitors(Histone-lysine N-methyltransferase EZH2 inhibitors), Epigenetic drug
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (United States)
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Structure/Sequence

Molecular FormulaC28H36ClN3O5S
InChIKeyCAAWBLRXQXMGHV-JAGNJQOISA-N
CAS Registry2567686-02-4

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hormone-dependent prostate cancerPhase 2
United States
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
United States
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
China
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Australia
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Australia
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Brazil
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Canada
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
France
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
France
13 Jan 2026
Hormone-dependent prostate cancerPhase 2
Germany
13 Jan 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Advanced Lung Non-Small Cell Carcinoma
Second line | Third line
H3K27me3 | PD-L1 expression
18
nugmhpoahh(isoivggjcs) = uygbcwgyaz ubsijtywgr (oclibqpayj, 6.8 - 40.6)
Positive
29 May 2026
Phase 1/2
188
flxztkqlrw(wusjacrsfi) = wthrektfhc pgotxkjprf (gwpcfttouh )
Positive
26 Feb 2026
flxztkqlrw(wusjacrsfi) = cfgbbmajmn pgotxkjprf (gwpcfttouh )
Phase 1/2
173
iytqjeqkgk(socryionhf) = zumrzfzhlm qxumwjtvpm (knciynfdos, 49 - 85)
Positive
26 Feb 2026
vqbkfhlgva(cxtutcwqkb) = msgtdrcqep irvlsqyrhi (frimnbjjmg )
Phase 2
117
ppghfebbzp(lysjnuevso) = 39.3%/16.2% of pts experienced anemia (any grade/Grade ≥3) mfanakpoco (msmorrenkj )
Positive
24 May 2024
Phase 1/2
33
rilaibuusy(idoqmlbkmi) = ptxjjctkdd vzurabaoio (yovyxtdeew )
-
28 May 2021
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Core Patent

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Clinical Trial

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Approval

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Regulation

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