Last update 04 Jul 2026

DV-281

Overview

Basic Info

Drug Type
CpG ODN
Synonyms
DV 281
Target
TLR9
Action
agonists
Mechanism
TLR9 agonists(Toll like receptor 9 agonists)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication-
Inactive Indication
Advanced Lung Non-Small Cell Carcinoma
Originator Organization
Dynavax Technologies Corp.Dynavax Technologies Corp.
Active Organization-
Inactive Organization
Dynavax Technologies Corp.Dynavax Technologies Corp.
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with DV-281
NCT03326752
/ CompletedPhase 1
Phase 1b Dose Escalation and Dose Expansion Trial of DV281 in Combination With an Approved Anti-PD-1 Inhibitor in Subjects With Advanced Non-Small Cell Lung Cancer
100 Clinical Results associated with DV-281
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100 Translational Medicine associated with DV-281
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100 Patents (Medical) associated with DV-281
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100 Deals associated with DV-281
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Lung Non-Small Cell CarcinomaPhase 1
United States
Dynavax Technologies Corp.Dynavax Technologies Corp.
20 Sep 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03326752 (Pubmed | Clin Cancer Res)
ManualManual
Phase 1
Non-Small Cell Lung Cancer
Second line
26
Nivolumab+DV281
xdivdmjxyl(wlwcyrmdxy) = gqulfzyyww psghrahuum (nsahldgnbg )
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Positive
15 Aug 2021
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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