[Translation] A single-center, randomized, double-blind, placebo-controlled, single-dose escalation phase I clinical study evaluating the safety, tolerability, pharmacokinetics, and immunogenicity of YF-3 injection in healthy adult subjects in China.
主要目的:评价中国健康成人受试者接受YF-3注射液单次静脉给药的安全性和耐受性,并确定最大耐受剂量。次要目的:评估中国健康成人受试者接受YF-3注射液单次静脉给药的药代动力学特征和免疫原性特征。
[Translation] Primary objective: To evaluate the safety and tolerability of a single intravenous administration of YF-3 injection in healthy Chinese adult subjects and to determine the maximum tolerated dose. Secondary objective: To assess the pharmacokinetic and immunogenic characteristics of a single intravenous administration of YF-3 injection in healthy Chinese adult subjects.