[Translation] A Phase I clinical study to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic characteristics, and bioavailability of XC2309 injection after single and multiple doses in healthy adult participants
评价在健康成年参与者中单次和多次静脉滴注XC2309注射液的安全性和耐受性、XC2309及其代谢产物的PK特征、PD特征;比较注射给药与口服给药的PK特征,评价口服生物利用度:比较多次静脉滴注XC2309注射液和注射用艾司奥美拉唑钠的PD特征。
[Translation] To evaluate the safety and tolerability of single and multiple intravenous infusions of XC2309 injection, the PK and PD characteristics of XC2309 and its metabolites in healthy adult participants; to compare the PK characteristics of injection and oral administration, and to evaluate oral bioavailability; and to compare the PD characteristics of multiple intravenous infusions of XC2309 injection and esomeprazole sodium for injection.