[Translation] A randomized, double-blind, crossover trial evaluating the accuracy, safety, and patient preference of a novel oral glucose solution compared to existing oral glucose powders for glucose tolerance testing.
主要目的:评价新型口服葡萄糖溶液与葡萄糖粉剂用于OGTT检查结果的一致性。次要目的:1) 比较受试者对两种葡萄糖制剂的偏好度;2) 评价新型口服葡萄糖溶液及已上市口服葡萄糖粉剂用于糖耐量检查的安全性、耐受性。3) 评价不同葡萄糖制剂对受试者血浆葡萄糖、胰岛素和 C 肽浓度的影响。
[Translation] Primary objective: To evaluate the consistency of results between a novel oral glucose solution and glucose powder for oral glucose tolerance tests (OGTT). Secondary objectives: 1) To compare subjects' preferences for the two glucose formulations; 2) To evaluate the safety and tolerability of the novel oral glucose solution and the marketed oral glucose powder for glucose tolerance tests; 3) To evaluate the effects of different glucose formulations on subjects' plasma glucose, insulin, and C-peptide concentrations.