Anhui Pioneer Pharmaceutical Co. Ltd.

This trial aimed to investigate the pharmacokinetic characteristics of ziprasidone hydrochloride capsules (20 mg) developed and produced by Anhui Pioneer Pharmaceutical Co., Ltd. after single oral administration on an empty stomach or after a meal in healthy study participants. Ziprasidone hydrochloride capsules (Zeldox®, 20 mg), licensed by Viatris Pharma GmbH and produced by Pfizer Ireland Pharmaceuticals, were used as the reference preparation. The pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞ were compared between the two preparations.

This study aimed to investigate the pharmacokinetic characteristics of dapagliflozin metformin extended-release tablets (dapagliflozin 10 mg (calculated as C21H25ClO6) and metformin hydrochloride 1000 mg) developed and produced by Anhui Pioneer Pharmaceutical Co., Ltd. after single fasting and postprandial oral administration in healthy study participants; dapagliflozin metformin extended-release tablets (Ⅰ) (Anda-Sol®, 10 mg/1000 mg) produced by AstraZeneca Pharmaceuticals LP was used as the reference preparation, and the pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞ of the two preparations were compared to evaluate the bioequivalence of the two preparations in humans.

The aim of this study was to investigate the pharmacokinetic characteristics of clindamycin palmitate hydrochloride granules (75 mg/5 ml calculated as clindamycin (C18H33ClN2O5S)) and clindamycin palmitate hydrochloride granules (75 mg calculated as clindamycin (C18H33ClN2O5S)) developed and produced by Anhui Pioneer Pharmaceutical Co., Ltd. after single oral administration on an empty stomach or after a meal. Clindamycin palmitate hydrochloride granules (Cleocin Pediatric®, 75 mg/5 ml calculated as clindamycin (C18H33ClN2O5S) produced by Pharmacia & Upjohn Company LLC were used as the reference preparation. The pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞ of the test preparation were compared with those of the reference preparation, and the bioequivalence of the test preparation with the reference preparation was evaluated.