Comparison of efficacy and safety of nanostructured lipid carriers loaded with Dutasteride and pumpkin seed oil and oily solution containing Dutasteride and pumpkin seed oil for androgenic hair loss pattern

Start Date21 Apr 2025

Sponsor / Collaborator

Tabriz University of Medical Sciences

RBR-10yfb37g

/ RecruitingPhase 2IIT

Mesotherapy with Dutasteride 0,1% versus Placebo for treatment of Male Androgenetic Alopecia: randomized clinic trial

Start Date01 Mar 2025

Sponsor / Collaborator-

100 Clinical Results associated with Dutasteride

100 Translational Medicine associated with Dutasteride

100 Patents (Medical) associated with Dutasteride

1,155

Literatures (Medical) associated with Dutasteride

31 Dec 2026·JOURNAL OF DERMATOLOGICAL TREATMENT

Oral finasteride use and sexual adverse events: signal detection from disproportionality analyses of data from the United States Food and Drug Administration Adverse Event Reporting System

Article

Author: Williams, Greg ; Bamimore, Mary A. ; Gupta, Aditya K. ; Talukder, Mesbah

BACKGROUND:

Oral finasteride 1 milligram (1 mg) daily-which is a 5-alpha reductase inhibitor (5-ARI) approved by the Food and Drug Administration (FDA) for androgenetic alopecia-is linked to sexual adverse events (AEs). However, it remains unclear whether this link is causal or merely correlational.

METHODS:

In FAERS, AEs are described by preferred terms (pts) of the Medical Dictionary for Regulatory Activities system; we investigated 8 AEs, including erectile dysfunction (pt = 10,061,461). We determined if signals could be detected with finasteride 1 mg-and 0.5 mg of dutasteride (a more potent 5-ARI)-in FAERS, for sexual AEs related to the post-finasteride syndrome (PFS): for the two, we identified the yearly number of cases (i.e. reports with sexual AEs) from 2006 to 2024. For each AE, we conducted a disproportionality analysis where reporting odds ratios (RORs) were estimated-along with p-values and 95% confidence intervals (CIs).

RESULTS:

There were more reports with finasteride 1 mg than with dutasteride 0.5 mg; for both, more reporting was observed as of 2012, the year the PFS foundation formally propagated PFS awareness.

CONCLUSIONS:

Our findings support that the disproportionately higher reporting of sexual AEs with finasteride 1 mg than with dutasteride 0.5 mg-even more so after 2012-could be attributed to the nocebo effect.

01 Jan 2026·INTERNATIONAL JOURNAL OF DERMATOLOGY

Is the Safety of Finasteride Correlated With Its Route of Administration: Topical Versus Oral? A Pharmacovigilance Study With Data From the United States Food and Drug Administration Adverse Event Reporting System

Article

Author: Keene, Sharon A. ; Bamimore, Mary A. ; Gupta, Aditya K. ; Talukder, Mesbah

ABSTRACT:

Background:

The United States Food and Drug Administration (FDA) approved oral finasteride for androgenetic alopecia. In 2022, approximately 2.6 million U.S. men used it for hair loss and prostate conditions. Post‐finasteride syndrome (PFS), proposed in 2012, involves persistent sexual and neuropsychiatric adverse events (AEs) after cessation. These AEs are controversial and often lack assessment of contributing risk factors. We analyzed FDA Adverse Event Reporting System (FAERS) data to explore finasteride's administration route and PFS‐like AEs.

Methods:

Using the information component (IC) method for disproportionality analyses, we assessed signals for 13 PFS‐related AEs with topical and oral finasteride and dutasteride across two periods: 2006–2011 (pre‐PFS reporting) and 2019–2024 (post‐PFS reporting). These periods reflect times before and after formal PFS reporting in 2012. Eight analyses per AE were conducted based on agent, route, and era.

Results:

Fewer signals for PFS‐like AEs were detected with topical finasteride compared to oral finasteride in both eras. No signals were found for topical dutasteride, possibly because its use is very limited. Many reported AEs, such as erectile dysfunction and depression, may be influenced by age, stress, or comorbidities.

Conclusions:

Signals for PFS‐like AEs were detected with topical finasteride, but were less frequent than with oral finasteride. The high prevalence of these AEs in the general population and the influence of confounding factors, such as psychological stress or nocebo effects, combined with the lack of genotyping, hormonal assessments, or family history data in most reports, suggest caution in attributing causality to finasteride. Topical finasteride may pose a lower risk, but robust evidence is needed to clarify its safety profile.

01 Jan 2026·Actas Dermo-Sifiliograficas

Consensus Document on the Clinical Management of Frontal Fibrosing Alopecia: Recommendations From Spanish Working Group on Trichology and Onychology of the AEDV

Review

Author: Porriño-Bustamante, M L ; Vañó-Galván, S ; Pindado-Ortega, C ; Combalia, A ; Fernandez-Crehuet, P ; Saceda-Corralo, D ; Serrano, C ; Garnacho, G

Frontal fibrosing alopecia (FFA) is a scarring alopecia first described in 1994. Due to its increasing incidence rate in dermatology clinics, and the scarcity of approved specific treatments, the diagnosis and treatment of FFA can be an increasingly common challenge for dermatologists in their routine daily practice. This FFA management consensus was produced via a Delphi methodology involving 22 dermatologists from the Spanish working group on trichology and onychology of the AEDV. Because hair loss is irreversible, multimodal therapy with complementary mechanisms and routes should be used starting with oral dutasteride along with topical and/or intralesional agents; if inflammation persists, hydroxychloroquine should be added to the mix.

News (Medical) associated with Dutasteride

01 Nov 2025

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True North Metabolic Expands Testosterone Replacement Therapy in Kitchener-Waterloo

Physician-led TRT program adds structured assessment, monitoring, and treatment options for men across Kitchener-Waterloo, Cambridge, and Guelph, Ontario. KITCHENER, ONTARIO, CANADA, November 1, 2025 / EINPresswire.com / -- True North Metabolic announced the expansion of its physician-led Testosterone Replacement Therapy (TRT) service for residents of Kitchener-Waterloo, Cambridge, and Guelph, Ontario, delivering a clear, evidence-based pathway from assessment to ongoing care. The program centralizes men’s health evaluation, lab timing guidance, therapy selection, and structured monitoring to help patients achieve symptom relief while maintaining safety. Service information is available at: • Men’s Health overview: https://www.truenorthmetabolic.com/kitchener-waterloo-men-s-health • TRT service page: https://www.truenorthmetabolic.com/kitchener-testosterone-replacement-therapy A Physician-Led, Mechanism-Focused Approach True North Metabolic’s care model emphasizes the mechanisms behind hypogonadism and the practical realities of daily treatment. Patients begin with a structured intake that documents symptoms (libido, energy, sleep, mood, body composition), medical history, and medications, followed by targeted morning labs and confirmatory testing when indicated. The clinic’s protocol aligns therapy with physiology—beginning only when diagnostic criteria are met—and pairs treatment with scheduled follow-ups to evaluate benefits, side effects, and adherence. Why TRT, and For Whom TRT may be appropriate for men with persistent symptoms and repeatedly low morning testosterone levels. The clinic counsels on realistic goals: improved sexual function, energy, strength, and sleep quality, while monitoring for potential risks such as erythrocytosis, blood pressure or lipid changes, fertility suppression, acne, edema, or sleep apnea exacerbation. Patients in Kitchener-Waterloo, Cambridge, Ontario and Guelph, Ontario receive individualized care plans that consider work schedules, training demands, and family-building timelines. Therapy Options Tailored to Daily Life The clinic offers multiple TRT routes and helps men choose the option that matches their routine, personal preferences and monitoring preferences: Topical gel (once daily): convenient and steady levels; requires transfer precautions and consistent application. Intranasal gel (three times daily): rapid on/off kinetics with low transfer risk; ideal for flexible dose titration. Injections: Shorter-acting (cypionate/enanthate): weekly or twice-weekly dosing, intramuscular or subcutaneous; cost-effective with predictable levels. Long-acting undecanoate (IM): infrequent clinic dosing with stable levels and observation period. Oral testosterone undecanoate (capsules): limited availability; considered case-by-case with counseling on cost and expectations. The TRT program integrates lifestyle modifications so patients see durable improvements beyond the prescription. Safety, Monitoring, and Follow-Up True North Metabolic’s protocol schedules labs at predictable intervals: early rechecks and then at regular intervals. Monitoring includes hematocrit/hemoglobin, testosterone levels timed to route, PSA where indicated, lipids, and blood pressure. The clinic also screens for obstructive sleep apnea and explores fertility-preserving alternatives when family planning is a priority. Adverse effects are managed through dose adjustment, route changes, or coordinated specialty referral when needed. Care That Extends Beyond Testosterone Men often present with overlapping concerns—weight gain, metabolic risk, and hair loss—that affect confidence and long-term health. True North Metabolic connects TRT care to additional services so patients have a single, coherent plan: Weight Loss Clinic (Kitchener-Waterloo) : evidence-based nutrition programs and medication options when appropriate, with an emphasis on cardiometabolic risk and lean-mass preservation. Learn more: https://www.truenorthmetabolic.com/kitchener-waterloo-weight-loss-clinic Hair Loss Care: mechanism-focused plans for androgenic alopecia, including counseling on finasteride or dutasteride and topical minoxidil, with realistic timelines for stabilization and regrowth. Details: https://www.truenorthmetabolic.com/kitchener-waterloo-hair-loss By aligning men’s health, weight management, and hair loss care, the clinic helps patients in Kitchener-Waterloo, Cambridge, Ontario and Guelph, Ontario move toward performance, aesthetics, and longevity goals in a single, coordinated pathway. About Clinical Leadership The testosterone replacement therapy (TRT) service is overseen by Dr. Khashayar Farzam, whose practice focuses on metabolic health for all adults and pediatrics and in addition; men’s health services which focuses on TRT. Dr. Farzam’s guidance informs the clinic’s structured intake, diagnostic workflows, and longitudinal monitoring protocols. More information about clinical leadership is available at: https://www.truenorthmetabolic.com/our-doctors Access, Service Area, and Booking True North Metabolic serves patients across Kitchener-Waterloo, Cambridge, Ontario and Guelph,Ontario; with appointment times designed for busy professionals. The clinic provides clear next steps after each visit, including lab requisitions, follow-up dates, and route-specific instructions to help patients stay on track. Patients can self-refer for a TRT assessment or seek a referral from their primary care provider. What Patients Can Expect at a First Visit History and goals: a focused discussion on symptoms, training, sleep, and health priorities. Diagnostic testing: morning testosterone measurements on two separate days, plus targeted labs where indicated. Plan selection: route of administration (gel, intranasal, injection, or oral TU if appropriate) with education on dosing, application technique, and monitoring. Follow-up roadmap: scheduled rechecks, symptom scores, and coaching support for sustainable changes in energy, body composition, and performance. Community Focus: Kitchener-Waterloo, Cambridge, Ontario and Guelph, Ontario The clinic’s expansion reflects local demand for structured, physician-led men’s health services. By centralizing evaluation and care under one roof—and tying TRT to weight and hair loss services—True North Metabolic aims to set a regional standard that balances outcomes with safety and education. The model highlights early identification of contraindications, realistic counseling on timelines, and a practical approach to adherence. Call to Action Residents of Kitchener-Waterloo, Cambridge, Ontario and Guelph, Ontario seeking evidence-based TRT can review service details and request an assessment at: • Men’s Health overview: https://www.truenorthmetabolic.com/kitchener-waterloo-men-s-health • TRT program: https://www.truenorthmetabolic.com/kitchener-testosterone-replacement-therapy For related needs, explore: • Weight Loss Clinic: https://www.truenorthmetabolic.com/kitchener-waterloo-weight-loss-clinic • Hair Loss Care: https://www.truenorthmetabolic.com/kitchener-waterloo-hair-loss Media Contact True North Metabolic Kitchener, Ontario Web: https://www.truenorthmetabolic.com/kitchener-testosterone-replacement-therapy Phone: (226) 686-0119 Mike Souza KWC info@truenorthmetabolic.com Visit us on social media: LinkedIn Instagram Facebook Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.

27 Oct 2025

·www.einpresswire.com

True North Metabolic Expands Evidence-Based Hair Loss Treatment in Kitchener-Waterloo-Cambridge, Ontario

Physician-led program focuses on male pattern baldness mechanisms and proven therapies—finasteride, dutasteride, and minoxidil—in Kitchener-Waterloo. KITCHENER, ONTARIO, CANADA, October 27, 2025 / EINPresswire.com / -- True North Metabolic today announced the expansion of its physician-led hair loss treatment in Kitchener-Waterloo, offering a comprehensive, mechanism-driven program for men experiencing androgenic alopecia (male pattern baldness). The clinic’s protocol integrates diagnostic assessment with evidence-based therapies, including finasteride, dutasteride, and minoxidil, supported by ongoing follow-up and education. Full details are available at: https://www.truenorthmetabolic.com/kitchener-waterloo-hair-loss . Male pattern baldness is driven by the interaction between dihydrotestosterone (DHT) and genetically susceptible follicles, which shortens the hair growth phase and progressively miniaturizes follicles on the hairline and crown. True North Metabolic’s program is built around this biology. The care pathway begins with a structured history, pattern mapping, and targeted lab review when indicated, followed by a personalized plan that addresses both upstream hormone signaling and downstream follicle support. Program Highlights Mechanism-Focused Care: The clinic prioritizes the core drivers of androgenic alopecia—DHT, androgen receptor sensitivity, and follicular miniaturization—so each patient’s plan aims to stabilize loss before rebuilding density. There is also major emphasis on ruling out other causes of hair loss before concluding that the diagnosis is androgenic alopecia aka male pattern baldness. Evidence-Based Medications: Finasteride (selective type 2 5-alpha reductase inhibitor) to reduce scalp and serum DHT and slow miniaturization. Dutasteride (type 1 and type 2 5-alpha reductase inhibitor) as an option when additional DHT suppression is appropriate. Minoxidil (topical) to lengthen anagen, increase follicle size, and support regrowth; often paired with a DHT-lowering agent for synergy. Structured Follow-Up: Clear timelines for reassessment (typically 3, 6, and 12 months) to track density, shedding, and treatment adherence, with dose adjustments or adjuncts as needed. Lab tests: Ensuring no secondary causes such as hypothyroidism or iron deficiency Ruling out other causes of hair loss: Other causes can include telogen effluvium and alopecia areata Lifestyle and Scalp Health: Counseling on scalp care, medication routines, and factors that can magnify telogen shedding (e.g., severe calorie deficits, poor sleep), while emphasizing that androgenic alopecia is a biologically programmed process best managed early. Why This Matters in Kitchener-Waterloo Search interest for hair loss treatment in Kitchener-Waterloo continues to grow as more men seek reliable, medical guidance rather than one-size-fits-all products. True North Metabolic’s program is designed for clarity and consistency: patients know the mechanism being targeted, which interventions are expected to stabilize versus regrow, and when to anticipate visible changes. The clinic’s location and scheduling accommodate professionals across Kitchener, Waterloo, Cambridge, and surrounding communities. Review of Clinical Leadership The program is overseen by Dr. Khashayar Farzam, a physician with a strong focus on metabolic and men’s health. The clinic’s approach reflects a medical model: assess, plan, treat, and monitor—precisely aligned with the pathophysiology of androgenic alopecia. Patients can expect clear counseling on benefits, timelines, and maintenance, particularly around long-term strategies with finasteride, dutasteride, and minoxidil in Kitchener-Waterloo. Patient Journey and Expectations Assessment: Pattern mapping, history (onset, family history, shedding), medication review, and targeted labs when indicated. Plan: Selection of DHT-targeting therapy (finasteride or dutasteride) plus topical minoxidil, with education on application, adherence, and expected timelines. Select cases may require oral minoxidil after extensive risk and benefit discussion. Early Phase (0–8 weeks): Possible transient shedding as older telogen hairs cycle out; adherence and technique are reinforced. Consolidation (3–6 months): Stabilization is the first milestone; early thickening and improved coverage may be observed in many cases. Maintenance (6–12+ months): Ongoing improvements depend on consistent use and biology; stopping treatment typically allows the original pattern to resume. Plans are adjusted or escalated if goals are not met. Quality, Safety, and Monitoring True North Metabolic emphasizes informed consent, evidence-based dosing, and follow-up to evaluate response and tolerability. Patients receive guidance on what is typical versus what warrants reassessment, along with practical strategies for daily routines. The clinic also coordinates with family physicians when requested and provides treatment summaries upon consent. Access and Scheduling Residents seeking kitchener hair loss or waterloo hair loss solutions can book an assessment online or by phone. The clinic offers flexible visit formats and clear next steps after each appointment. The dedicated page—** https://www.truenorthmetabolic.com/kitchener-waterloo-hair-loss**—outlines the program structure, medication options, and frequently asked questions to help prospective patients prepare for hair loss treatment in Kitchener-Waterloo. About True North Metabolic True North Metabolic is a Kitchener-based clinic focused on metabolic health, men’s health, and evidence-based interventions for conditions that impact quality of life and performance. The clinic’s hair loss service integrates medical expertise with practical, stepwise care to help patients stabilize loss and pursue durable coverage. Call to Action For more information about hair loss treatment in Kitchener-Waterloo—including finasteride, dutasteride, and minoxidil in Kitchener-Waterloo—visit https://www.truenorthmetabolic.com/kitchener-waterloo-hair-loss or email the clinic at info@truenorthmetabolic.com Media Contact True North Metabolic Kitchener, Ontario Phone: (226) 686-0119 Web: https://www.truenorthmetabolic.com/kitchener-waterloo-hair-loss Mike Souza KWC email us here Visit us on social media: LinkedIn Instagram Facebook Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.

06 Jun 2025

·www.einpresswire.com

Understanding the Effects of Dihydrotestosterone (DHT) on the Prostate and Treatment Options for Elevated Levels

New Research Highlights DHT’s Role in Prostate Health and Emerging Therapies to Manage Hormone Imbalance Understanding the role of dihydrotestosterone (DHT) is essential for those undergoing testosterone replacement therapy.” — Chris Rue, FNP-C NEW ORLEANS, LA, UNITED STATES, June 6, 2025 / EINPresswire.com / -- Dihydrotestosterone (DHT), a potent androgen derived from testosterone, plays a critical role in the development and maintenance of male characteristics. However, medical experts and researchers are sounding the alarm about its potential impact on prostate health, especially when levels become elevated. DHT is primarily synthesized in the prostate, liver, skin, and hair follicles through the enzymatic conversion of testosterone by 5-alpha reductase. While essential for male development, excessive DHT levels have been strongly linked to benign prostatic hyperplasia (BPH) and an increased risk of prostate enlargement, which can lead to urinary problems and decreased quality of life in aging men. Effects of Elevated DHT on the Prostate: • Prostate Enlargement: Elevated DHT stimulates excessive growth of prostate tissue, contributing to BPH. • Urinary Symptoms: Increased prostate volume can compress the urethra, causing frequent urination, difficulty starting urination, and weak urinary flow. • Potential Cancer Risk: Though the relationship is complex, some studies suggest high DHT levels may influence prostate cancer progression. According to recent clinical reviews, men over the age of 50 are especially vulnerable, with over 50% developing some form of prostate enlargement by age 60. Treatment Options to Lower Elevated DHT Levels: Medical professionals emphasize early intervention and hormone regulation as key strategies. The most common treatments include: 1. 5-Alpha Reductase Inhibitors: Medications such as finasteride (Proscar) and dutasteride (Avodart) block the conversion of testosterone to DHT, reducing prostate size and alleviating symptoms. 2. Natural DHT Blockers: Compounds like saw palmetto extract, pumpkin seed oil, and green tea catechins are under investigation for their mild DHT-lowering effects. 3. Lifestyle Changes: A diet rich in anti-inflammatory foods, regular exercise, and weight management may help regulate hormone levels. 4. Hormonal Monitoring: Regular blood tests to track testosterone and DHT levels can aid in early detection and intervention. Dr. Michael Reynolds, a board-certified urologist, commented, “DHT is essential, but when imbalanced, it can become a catalyst for prostate issues. We now have evidence-based strategies to bring levels back to a healthier range.” About the Prostate Health Initiative The Prostate Health Initiative is a nationwide educational campaign aimed at raising awareness about male hormone balance and its effects on long-term urological health. Through collaboration with healthcare providers and research institutions, the initiative seeks to empower men to make informed choices about their prostate health. ________________________________________ Chris Rue Metairie Optimal Performance Enhancement +1 504-265-5491 info@mopeclinic.com Visit us on social media: LinkedIn Facebook Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.

100 Deals associated with Dutasteride

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KEGG	Wiki	ATC	Drug Bank
D03820	Dutasteride	G04CB02	DB01126

R&D Status

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Indication	Country/Location	Organization	Date
Androgenetic Alopecia	Japan	GSK Plc	28 Sep 2015
Prostatic Hyperplasia	United States	Waylis Therapeutics LLC	20 Nov 2001

Developing

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Adenocarcinoma of prostate	Phase 3	Canada	GSK Plc	01 Mar 2007
Localized Prostate Carcinoma	Phase 3	United States	GSK Plc	01 Nov 2005
Prostatic Cancer	Phase 3	United States	GSK Plc	01 Mar 2003
Prostatic Cancer	Phase 3	Japan	GSK Plc	01 Mar 2003
Prostatic Cancer	Phase 3	Argentina	GSK Plc	01 Mar 2003
Prostatic Cancer	Phase 3	Australia	GSK Plc	01 Mar 2003
Prostatic Cancer	Phase 3	Austria	GSK Plc	01 Mar 2003
Prostatic Cancer	Phase 3	Belarus	GSK Plc	01 Mar 2003
Prostatic Cancer	Phase 3	Belgium	GSK Plc	01 Mar 2003
Prostatic Cancer	Phase 3	Brazil	GSK Plc	01 Mar 2003

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT04098302 (CTgov)	Phase 2/3	Alcohol Use Disorder	180	Dutasteride Capsules (Dutasteride)	utufaiqvvg(dnujftbfgr) = jnqxswnudx ycnixdkffm (mlnhaewifv, 0.33) View more	-	09 May 2025
				Placebo Capsules (Placebo Capsule)	utufaiqvvg(dnujftbfgr) = lsctjnrlxo ycnixdkffm (mlnhaewifv, 0.28) View more
NCT02213107 (phase II trial of enzalutamide (Enz) with 5-alpha reductase inhibitors (5-ARI), CTgov)	Phase 2	Recurrent Prostate Carcinoma \| Prostatic Cancer \| Localized Prostate Carcinoma ... View more	43	finasteride+Enzalutamide+Dutasteride	yfukswadnd = ostdrquumq brizcspjzr (xtuhfsrwuk, qausoditdc - rglkfnhjcn) View more	-	13 Nov 2024
NCT02213107 (ASCO2024) Manual	Phase 2	Castration-sensitive prostate cancer	43	Enzalutamide 16Dutasteride+ DFinasteride0.5mg daily	eyydlnqnzv(zdjqdiammm) = fdpwhfoemo sgqkmcmgwl (hitnxribwh ) View more	Positive	24 May 2024
NCT01758523 (Pubmed)	Phase 4	Alcoholism	142	Dutasteride 1 mg	clkpudgixn(zqgvtfjahr) = Adverse events more common in the dutasteride group were reduced libido hljxcfvosd (pskmdjssfk ) View more	Positive	01 May 2024
				Placebo
NCT00668642 (CTgov)	Phase 2	Advanced Prostate Carcinoma	20	Dutasteride (A: Dutasteride During First Off-Cycle)	tqijnhyboe(qxkipuunmw) = cckbbkfymk bjhwlbvlnt (nxclbcbzwe, 0.5) View more	-	22 Aug 2023
				Placebo (B: Placebo During First Off-Cycle)	tqijnhyboe(qxkipuunmw) = jjdylqenzy bjhwlbvlnt (nxclbcbzwe, 0.45) View more
NCT01342367 (Prospective Trial Of Oral-Only Hormonal Therapy With Radiation, CTgov)	Not Applicable	Non-metastatic prostate cancer	74	bicalutamide+leuprolide+goserelin (SOC Cohort)	omdmgirkxj(fcgevyfxou) = ajdqzfszxp zziihhdgzt (qhcrggpzhi, 0.04) View more	-	28 Oct 2021
				finasteride+dutasteride+bicalutamide (Oral ADT Group)	omdmgirkxj(fcgevyfxou) = sralunijpn zziihhdgzt (qhcrggpzhi, 0.04) View more
NCT02213107 (ESMO2020)	Phase 2	Prostatic Cancer	43	Enzalutamide 160mg daily + Dutasteride 0.5mg daily	uqsoiknzps(prqnxexczw) = the most common any grade AE was fatigue (65%) phfdkhjjqb (tkdulpmwis ) View more	Positive	17 Sep 2020
				Enzalutamide 160mg daily + Finasteride 5mg daily
NCT02213107 (ASCO2019)	Phase 2	Prostatic Cancer	43	Enzalutamide 160 mg/day + Dutasteride 0.5 mg/day	khbmcagjnc(tykwajfmej) = ovhynfkspl idpburwgxt (stsljtxptw ) View more	Positive	26 May 2019
NCT01758523 (CTgov)	Phase 4	Alcoholism	189	Dutasteride (Dutasteride)	djwmylaqcr(bqqbtmttic) = kiadmokssz avbhxwdxys (lqkdgywmnc, 0.33) View more	-	26 Apr 2019
				sugar pill (Sugar Pill)	djwmylaqcr(bqqbtmttic) = sepzubhsrs avbhxwdxys (lqkdgywmnc, 0.34) View more
NCT02058368 (CTgov)	Phase 3	Prostatic Hyperplasia	607	Placebo (Placebo + Tam 0.2mg)	cracjxafeg(trydddfjny) = ngsmnzpott qkfsmghxll (ehgudptnmz, 0.34) View more	-	05 Apr 2019
				Dut (Dut 0.5 mg + Tam 0.2 mg)	cracjxafeg(trydddfjny) = rdpxyznmfp qkfsmghxll (ehgudptnmz, 0.34) View more

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