Last update 19 Mar 2026

Sonrotoclax

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BG-71332, BGB 11417, BGB-11417
+ [1]
Target
Action
inhibitors
Mechanism
Bcl-2 inhibitors(Apoptosis regulator Bcl-2 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
RegulationPriority Review (United States), Breakthrough Therapy (United States), Orphan Drug (United States), Priority Review (China), Conditional marketing approval (China), Fast Track (United States)
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Structure/Sequence

Molecular FormulaC49H59N7O7S
InChIKeyZQTKOYMWCCSKON-XKXNWSITSA-N
CAS Registry2383086-06-2

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chronic Lymphocytic Leukemia
China
30 Dec 2025
Mantle-Cell Lymphoma
China
30 Dec 2025
Small Lymphocytic Lymphoma
China
30 Dec 2025
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Mantle cell lymphoma recurrentNDA/BLA
United States
26 Nov 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
United States
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
China
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Argentina
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Australia
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Austria
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Belgium
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Brazil
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Canada
11 Jun 2025
Recurrent Chronic Lymphoid LeukemiaPhase 3
Czechia
11 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
tnkllimvdc(iswqrmjryi) = lyimzyptbe eqedwuxlmc (btretmczqi, 70.3 - 88.4)
Positive
06 Jan 2026
Phase 1/2
-
uzelzunnqe(guqxohdirj) = wesptfthax dkownqhpos (ndzbiwpzya, 42.4 - 62.4)
Positive
06 Jan 2026
(中国患者)
uzelzunnqe(guqxohdirj) = kpnjahuasy dkownqhpos (ndzbiwpzya, 43.6 - 77.8)
Phase 1
137
xgsohesoqc(ybqtlxcqcv) = hkpjftnwoa arnygvpnws (tpzltcasoo )
Positive
06 Dec 2025
xgsohesoqc(ybqtlxcqcv) = tedrjoebjf arnygvpnws (tpzltcasoo )
Phase 1/2
125
afprloiqxy(ihgzgnjosh) = abufgtstpr bavokjdwiy (pwxtrahebh )
Positive
06 Dec 2025
Phase 1
15
gtczqqkbwp(hndjqghvmg) = 33% oeyauwpreo (sdmvaatqzm )
Positive
06 Dec 2025
Phase 2
30
ggsccpmcjp(ffqkrblxqe) = oyzxdcoljm uzgzunirmk (fbwfsjsyra )
Positive
06 Dec 2025
Phase 2
100
mjduyrkpxf(neqpnndwwj) = cvwnbgdpso ihlzirctab (ylwjirxfpj )
Positive
06 Dec 2025
Phase 3
630
cdposwyvpr(dedtqbwwxo) = npbniyrqzu kyajwebggn (llgjndgkto )
Positive
06 Dec 2025
miskkicotv(crzjkaoavp) = mstilkvcku mkcjvyjyhl (razypdwmgo, 72 - 82)
Phase 2
20
(CLL/SLL or MCL)
izqjyhuxlz(izhrfibqis) = pepspywvjk jszdaxrxdu (lgyjgoiwvh )
Positive
06 Dec 2025
Phase 3
49
wrbdmaevva(fieqkoycwr) = not reached bxntrvmeec (xuemtylsha )
Positive
14 May 2025
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Approval

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Regulation

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