Last update 13 Aug 2026

Vantictumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-frizzled receptor monoclonal antibody, Anti-Fzd receptor monoclonal antibody, Anti-Fzd7 receptor monoclonal antibody
+ [3]
Target
Action
inhibitors
Mechanism
FZD7 inhibitors(frizzled class receptor 7 inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D10410Vantictumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic breast cancerPhase 1
United States
01 Sep 2013
Pancreatic Ductal AdenocarcinomaPhase 1
United States
01 Sep 2013
Recurrent Non-Small Cell Lung CancerPhase 1
United States
01 Sep 2013
Solid tumorPhase 1
United States
-01 May 2011
Breast CancerPhase 1--
Non-Small Cell Lung CancerPhase 1--
Pancreatic CancerPhase 1--
Osteopetrosis Autosomal Dominant Type 2Preclinical
United States
01 Apr 2026
OsteopetrosisPreclinical
United States
01 Dec 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
48
epinbzumef(mhbauyutgm) = sfkwcvdqzh wgtywfdlqz (tsqpiazwjx )
Positive
01 Nov 2020
Phase 1
31
vezkgfiplx(yqwokemtny) = not determined katjmldayb (vvsntpevyv )
Negative
01 Jun 2020
Phase 1
31
Vantictumab + Nab-P + G
nasytjcbwb(dllhzhhdpi) = grade 3 dehydration in 1 of 9 patients in cohort 4 (5 mg/kg q4w) bfhsdreuyq (tpjnkwdkke )
Negative
29 Jan 2019
Phase 1
23
upzhftjvgq(gibjcjfqeo) = n = 3 ofenahmujs (yyylszgmln )
-
20 May 2016
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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